While calcium deposits in the shoulder tendons (calcific tendinitis) is not a particularly common condition, when the area where calcium has accumulated becomes inflamed, it can cause severe pain and discomfort. Calcium deposits can form in any tendon in the body, such as in the shoulders, ankles, and knees, but they most often cause serious pain in the shoulder rotator cuff tendon used to lift the arm, known as the supraspinatus tendon.