There are a number of symptoms that originate in the esophagus. These include difficulty swallowing food, heartburn, and chest pain. Additionally, an x-ray (barium swallow or upper GI series) or endoscopy may show abnormalities that need to be studied further by manometry. The exam is often done before and after medical or surgical treatments of the esophagus. Esophageal manometry is very effective in evaluating the difficulty in swallowing or heartburn and chest pain.