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Clear
 
Test Code:
090-40-0910-01

Order Name:
Tzanck Test

 
Useful For:
Useful test for diagnosis of cutaneous dermatoses
 
Methodology:
Microscopic Wright-Giemsa stain
 
AliasesName:
Multinucleated giant cell Tzanck smear
 
 
 
Test Code:
090-40-0910-01

Order Name:
Tzanck Test

 
Collection Specimen Or Container:
Vesicular scrape from Skin or Lip/ Microscopic slide
 
Specimen Testing Type:
Vesicular scrape from Skin or Lip/ volume Entire collection
 
Sub Mission Container:
Apply original sample to surface of Microscopic slide using appropriate application method (determined by consistency of specimen type)
 
Specimen Stabillity:
Specimen Type Temperature Time
Vesicular scrape Room temperature, 18oC to 25oC 24 hours
 
 
 
Test Code:
090-40-0910-01

Order Name:
Tzanck Test

 
Method detail:
Microscopic Wright-Giemsa stain
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Received specimen to reported within 3 hours.
 
Performing Location:
Microbiology, Laboratory Department Tel. 14171
 
Specimen Retention Time:
7 days
 
 
 
Test Code:
090-40-0910-01

Order Name:
Tzanck Test

 
 
Clinical Information:
The Tzanck smear is mainly used in an acute setting to rapidly detect a herpes infection or to distinguish Stevens- Johnson syndrome / toxic epidermal necrolysis (SJS/TEN) from Staphylococcal scalded skin syndrome. However, it can be used to diagnose a variety cutaneous infections and blistering diseases.
 
Reference Value:
No Multinucleated giant cell seen
 
Interpretation:
Tzanck cells (Multinucleated giant cell) are found in: Herpes simplex Varicella and herpes zoster Pemphigus vulgaris Cytomegalovirus
 
Clinical Reference:
  1. Amy L. Leber, editor. Clinical Microbiology Procedure Handbook 4th Edition. Washington DC: American Society for Microbiology; 2016
  2. James H. Jorgensen, Michael A. PFALLER. Manual of Clinical Microbiology 11th ed. Washington, DC: ASM Press; 2015
  3. http://webdb.dmsc.moph.go.th/ifc_nih/applications/pics/Herpes.html