Test Code (รหัสการทดสอบ):
Order Name (ชื่อการทดสอบ):
Clinical Information (ข้อมูลทางคลินิก):
Cardiac troponin T (cTnT) is an independent prognostic marker which can predict the near-, mid- and even long‑term outcome of patients with acute coronary syndrome (ACS). Cardiac troponin has been reconfirmed as the preferred marker of myocardial injury in the new guidelines for the diagnosis and treatment of non‑ST‑segment elevation acute coronary syndromes. Troponins are released during the process of myocyte necrosis. While they are cardiac specific, they are not specific of MI only. To distinguish between acute and chronic cTn elevations, the Universal Definition of AMI requires the need for serial sampling to observe a rise and/or fall of cTn above the 99th percentile upper reference limit. Absolute changes in cTn appear to
have a higher diagnostic accuracy for AMI compared to relative changes.Results interpretation have to be analyzed integrating the clinical assessment, including ischemic symptoms and electrocardiographic changes.
Elevated levels of troponin T correlate with the severity of coronary artery disease and to poor outcome independent of natriuretic peptide (NT‑proBNP or BNP) levels. Myocardial cell injury leading to elevated cTnT concentrations in the blood can also occur in other clinical conditions such as myocarditis,heart contusion, pulmonary embolism and drug‑induced cardiotoxicity.
Low concentrations of troponin T are an independent predictor of cardiovascular events including occurrence and recurrence of atrial fibrillation.
Reference Value (ค่าอ้างอิง):
0.00 - 0.013 ng/mL (ug/L)
Clinical Reference (เอกสารอ้างอิง):
Manufacturer’s Reagent package insert, Elecsys and cobas e analyzers Troponin T, 2018-11, V.9, Roche Diagnostics GmbH, Sandhofer Strasse 116, D-68305 Mannheim.