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Test Code (รหัสการทดสอบ):
PROL

Order Name (ชื่อการทดสอบ):
Prolactin

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to reported within 2:00 Hours (120 Mins)
 
Useful For (ประโยชน์การทดสอบ):
Determination of prolactin in human serum.

An aid in the diagnosis of male and female infertility and pituitary dysfunction, monitoring of male and female gonadal disorders and management of amenorrhea and galactorrhea.
 
Methodology (วิธีการทดสอบ):
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
 
 
Test Code (รหัสการทดสอบ):
PROL

Order Name (ชื่อการทดสอบ):
Prolactin

 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 1 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic vial
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Hemolysis: 4+ reject
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum (keep in original tube) Refrigerated, 2oC to 8oC 72 hours
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -10oC 12 months
 
 
 
Test Code (รหัสการทดสอบ):
PROL

Order Name (ชื่อการทดสอบ):
Prolactin

 
Method detail (วิธีการทดสอบ):
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
Schedule (ตารางการทดสอบ):
Tested Daily (24 Hours)
 
Turnaround Time (ระยะเวลารอผล):
Specimen collected to reported within 2:00 Hours (120 Mins)
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Immunology, Laboratory Department Tel. 13227
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
PROL

Order Name (ชื่อการทดสอบ):
Prolactin

 
 
Clinical Information (ข้อมูลทางคลินิก):
 Human prolactin (hPRL) is a single chain polypeptide of 199 amino acids and a molecular weight of approximately 23,000 daltons. Its existence as a distinct chemical entity, separate from growth hormone, was established through a series of studies between 1965 and 1971. Prolactin is produced by the anterior pituitary and its secretion is regulated physiologically by inhibitory and releasing  factors of the hypothalamus. Prolactin appears in the blood promptly after administration of thyrotropin-releasing hormone (TRH). The major physiologic action of prolactin is the initiation and maintenance of lactation in women.

Hyperprolactinemia has been established as a common cause of infertility and gonadal disorders in men and women. Prolactin has been shown to inhibit the secretion of ovarian steroids  and to interfere with follicle
maturation  and the secretion of LH and FSH  in the human female. Measurement of elevated serum prolactin levels may provide the first quantitative evidence of pituitary dysfunction. Quantitation of prolactin levels is also of interest in the evaluation and management of patients with amenorrhea and galactorrhea.

Various factors other than disease states have been found to influence prolactin levels. Factors which increase prolactin concentrations include: pregnancy, breast stimulation, stress, coitus, administration of estrogens, progesterone, androgens, some psychotropic and antihypertensive drugs, and TRH. Factors which decrease prolactin concentrations include the administration of L-dopa and bromocriptine.
 
 
Reference Value (ค่าอ้างอิง):
Men : 3.46 – 19.40  ng/mL 
Women : 5.18 – 26.53 ng/mL
 
Clinical Reference (เอกสารอ้างอิง):
Manufacturer’s Reagent package insert Architect Prolactin, January 2016,  Abbott Ireland Diagnostics Division, Lisnamuck, Longford Co.,Longford,Ireland