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Test Code (รหัสการทดสอบ):
LAB27

Order Name (ชื่อการทดสอบ):
Package BH MedGene

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/K3 EDTA (Lavender Top) 3 mL, 1 tube หรือ

Buccal swab 1 swab

Document required:
1. Completed Consent form LAB-08170-Rev03-EN-Consent-for-Genomic-Medicine-Testing.pdf
2. Completed Requisition form 9-10-11-PGx_Instruction-and-Requisition-form-V-Jun2023.pdf
 
Turnaround Time (ระยะเวลารอผล):
Reported within 21 days
 
Useful For (ประโยชน์การทดสอบ):
Pharmacogenomics (PGx) lab testing has become increasingly useful for precision medicined as it help to tailor medicine treatment for individual person.  This panel specifically identifies patients who may be at risk for altered metabolism of drugs that are modified by CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, OPRM1, SLCO1B1, and VKORC1.

Please find information sheet from this link below
BH-MedGene_TH-(4).pdf
BH-MedGene_EN-(3).pdf

 
 
Methodology (วิธีการทดสอบ):
Next generation sequencing (NGS)
 
Test List In Profile (การทดสอบใน Profile):
Nine genes: CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, OPRM1, SLCO1B1, and VKORC1.
Including Pharmacy Personalized Report
 
AliasesName (ชื่อเรียกอื่นๆ) :
PGX,  Pharmacogenetics, Pharmacogenomics,
CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, OPRM1, SLCO1B1, and VKORC1.
 
 
 
Test Code (รหัสการทดสอบ):
LAB27

Order Name (ชื่อการทดสอบ):
Package BH MedGene

 
Patient Preparation (การเตรียมตัวผู้ป่วย):
งดการรับประทานอาหารและเครื่องดื่ม (ยกเว้นน้ำเปล่า) งดการสูบบุหรี่ งดการแปรงฟันหรือเคี้ยวหมากฝรั่ง ก่อนเก็บตัวอย่าง 1 ชั่วโมง
 
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):

Blood/K3 EDTA (Lavender Top) 3 mL, 1 tube หรือ

Buccal swab 1 swab

Document required:
1. Completed Consent form LAB-08170-Rev03-EN-Consent-for-Genomic-Medicine-Testing.pdf
2. Completed Requisition form 9-10-11-PGx_Instruction-and-Requisition-form-V-Jun2023.pdf
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):

Blood/K3 EDTA (Lavender Top) 3 mL, 1 tube หรือ

Buccal swab 1 swab
 
Sub Mission Container (ภาชนะส่งตรวจ):
EDTA (Lavender Top) หรือ
Buccal swab
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
No sticker label on swab
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Buccal swab is ready to use and does not require additional preparation. It must be stored in its original package at a temperature between 2 and 30°C until the time of use. Do not overheat. Do not incubate or freeze prior to use. If incorrectly stored, its effectiveness will be compromised. Do not use after the expiry date clearly printed on the tube and on each single package. The sample must be collected immediately after opening the transparent bag.
 
 
 
Test Code (รหัสการทดสอบ):
LAB27

Order Name (ชื่อการทดสอบ):
Package BH MedGene

 
Turnaround Time (ระยะเวลารอผล):
Reported within 21 days
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Clinical Genomics Lab, Tel 14252.
PGx Drug information, Tel. 41919.
 
 
 
Test Code (รหัสการทดสอบ):
LAB27

Order Name (ชื่อการทดสอบ):
Package BH MedGene

 
 
Clinical Information (ข้อมูลทางคลินิก):
Pharmacogenomics (PGx) lab testing has become increasingly useful in the managing of medications in clinical practice. By utilizing PGx lab test results, clinicians may now more accurately determine how a patient can metabolize certain medications to assist in identifying whether a medication will not work, work as expected or cause adverse drug reactions (ADRs) that may result in increased morbidity or mortality. This testing covers genes which control descriptive P-450 enzymes or CYP enzymes, primarily located in the small intestine and liver and sometimes other genes such as HLA genes.  Pharmacogenomic (PGx) testing can help avoid adverse drug reactions (ADRs) or medication inefficacy by assisting in the adjustment of current or future medication doses. It can also help predict the best medications to use or those to avoid in advance by eliminating much of the existing dosing or medication selection method of trial and error

Please find example report from this link below
9-1-Future-medication-lists_Database.pdf
9-2-Current-medication_Personalized.pdf
9-3-Future-medication-summary_TrakCare.pdf
9-4-Future-drug-herb-interaction-(New).pdf
 
Clinical Reference (เอกสารอ้างอิง):
1. Cacabelos R, Naidoo V, Corzo L, Cacabelos N, Carril JC. Genophenotypic Factors and Pharmacogenomics in Adverse Drug Reactions. Int J Mol Sci. 2021 Dec 10;22(24):13302. doi: 10.3390/ijms222413302.