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Test Code:
090-91-0024-01

Order Name:
POCT - Creatinine & eGFR (MDRD equation)

 
Useful For:
For the quantitative determination of creatinine in whole blood
 
Methodology:
Amperometric assay, i-STAT1 analyzer
 
Test List In Profile:
POCT Creatinine
 
AliasesName:
i-STAT Creatinine
POCT Creatinine
 
 
 
Test Code:
090-91-0024-01

Order Name:
POCT - Creatinine & eGFR (MDRD equation)

 
Collection Specimen Or Container:
The specimens can be selected as list below:
  1. Fresh Venous blood / Plain syringe or
  2. Blood / Lithium heparin (Green Top) 6 mL., 1 tube
 
Specimen Testing Type:
  1. Fresh Venous blood from plain syringe, Test volume 65 uL
  2. Heparinized whole blood, Test volume 65 uL
 
Rejection Criteria:
  1. Clotted specimen will be reject.
  2. Wrong specimen container will be reject.
 
Specimen Stabillity:
Specimen Type Time
Venous from plain syringe Immediately testing
Heparinized whole blood specimen Can be test within 30 minutes
 
 
 
Test Code:
090-91-0024-01

Order Name:
POCT - Creatinine & eGFR (MDRD equation)

 
Method detail:
Creatinine is hydrolyzed to creatine in a reaction catalyzed by the enzyme creatinine amidohydrolase. Creatine is then hydrolyzed to sarcosine in a reaction catalyzed by the enzyme creatine amidinohydrolase. The oxidation of sarcosine, catalyzed by the enzyme sarcosine oxidase, produces hydrogen peroxide. The liberated hydrogen peroxide is oxidized at the platinum electrode to produce a current which is proportional to the creatinine concentration.
 
Schedule:
Test Daily at 07:00 - 23:00 (Only provided at CT-MRI Department)
 
Turnaround Time:
Collected specimen to report within 5 minutes (Bedside testing)
 
Performing Location:
POCT, CT-MRI Department
 
 
 
Test Code:
090-91-0024-01

Order Name:
POCT - Creatinine & eGFR (MDRD equation)

 
 
Clinical Information:
Elevated levels of creatinine are mainly associated with abnormal renal function and occur whenever there is a significant reduction in glomerular filtration rate or when urine elimination is obstructed.

The concentration of creatinine is a better indicator of renal function than urea or uric acid because it is not affected by diet, exercise, or hormones.

The creatinine level has been used in combination with BUN to differentiate between prerenal and renal causes of an elevated urea/BUN.
 
Reference Value:
Sex Reference Value Unit
Male 0.73 - 1.18 mg/dL
Female 0.55 - 1.02 mg/dL
 
Clinical Reference:
  1. i-STAT 1 User Guide; 2010, Abbott Point of Care Inc. Abbott Park, IL 60064, USA.
  2. i-STAT 1 System Manual for Waived Test; 2010, Abbott Point of Care Inc. Abbott Park, IL 60064,USA. Park, IL 60064, USA.
  3. i-STAT Cartridge and test information; 2010, Abbott Point of Care Inc. Abbott Park, IL 60064, USA.