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Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
092-10-0112
Order Name (ชื่อการทดสอบ):
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
PBS in Sterile PCR tube

Document required:
Consent Form for Preimplantation Genetic Screening/Diagnosis of Embryos
Questionnaire for Preimplantation Genetic Testing for Aneuploidy

For B2B: Requistion and Consent Form for PGT-A, Please click LINK
 
Turnaround Time (ระยะเวลารอผล):
Report within 10 days
 
Useful For (ประโยชน์การทดสอบ):
Preimplantation Genetic Testing for Aneuploidy
 
Methodology (วิธีการทดสอบ):
Next generation sequencing (NGS)
 
AliasesName (ชื่อเรียกอื่นๆ) :
PGS
 
 
 
Test Code (รหัสการทดสอบ):
092-10-0112
Order Name (ชื่อการทดสอบ):
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
 
Patient Preparation (การเตรียมตัวผู้ป่วย):
Women undergoing IVF to have a biopsy of an embryo. Please consult IVF center before ordering this test
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
PBS in Sterile PCR tube

Document required:
Consent Form for Preimplantation Genetic Screening/Diagnosis of Embryos
Questionnaire for Preimplantation Genetic Testing for Aneuploidy

For B2B: Requistion and Consent Form for PGT-A, Please click LINK
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Embryo biopsy of Day 3, Day 5, Day 6
 
Sub Mission Container (ภาชนะส่งตรวจ):
PBS in Sterile PCR tube
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Store at -20°C  within 1 Week
 
 
 
Test Code (รหัสการทดสอบ):
092-10-0112
Order Name (ชื่อการทดสอบ):
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
 
Turnaround Time (ระยะเวลารอผล):
Report within 10 days
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Clinical Genomics Tel. 14252
 
 
 
Test Code (รหัสการทดสอบ):
092-10-0112
Order Name (ชื่อการทดสอบ):
PGT-A (Preimplantation Genetic Testing for Aneuploidy)
 
 
Clinical Information (ข้อมูลทางคลินิก):
Preimplantation Genetic Testing for Aneuploidy (PGT-A) is a screening method used with IVF or ICSI to detect chromosomal abnormalities in embryos before implantation. A small number of cells are randomly aspirated or biopsied from embryos at either the cleavage stage (6–8 cells, on day 3 after egg retrieval) or the blastocyst stage (day 5 after egg retrieval). These cells are analyzed using Next Generation Sequencing (NGS) technology. The goal is to select euploid embryos for transfer, ensuring they are healthy and at low risk for genetic disorders like Down syndrome. PGT-A benefits infertile couples, women with recurrent miscarriages, and those with failed IVF attempts by lowering miscarriage risk, reducing IVF cycles, and increasing pregnancy success rates.

Limitations and Risks: PGT-A cannot detect all chromosomal abnormalities and may yield false results due to mosaicism. Standard prenatal testing is still recommended. Insufficient genetic material or poor quality can lead to inconclusive results. There is a small risk of embryo loss or reduced implantation potential. Long-term effects are still being studied, but current data show no increased abnormalities compared to conventional assisted reproductive technologies.
 
Clinical Reference (เอกสารอ้างอิง):
• Mayo Clinic. In vitro fertilization (IVF). Available from: https://www.mayoclinic.org/tests-procedures/in-vitro-fertilization/about/pac-20384716 [Accessed 5 June 2024].
• Healthline. In vitro fertilization (IVF). Available from: https://www.healthline.com/health/in-vitro-fertilization-ivf [Accessed 5 June 2024].
• The Protection of Children Born by Assisted Reproductive Technology Act, B. E. 2558
• “Treatment by Assisted Reproductive Technology” Consent Form, the Royal Thai College of Obstetricians and Gynecologists