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Clear
 
Test Code:
090-10-0350-04

Order Name:
Lupus Anticoagulant

 
Useful For:
Detecting and confirming or helping to exclude the presence of lupus anticoagulants (LA)
 
Methodology:
Silica Clotting Time (SCT)
Diluted Russell’s Viper Venom test
 
AliasesName:
Dilute Russell Viper Venom Time (DRVVT)
DRVVT (Dilute Russell Viper Venom Time)
Phospholipid Antibodies
 
 
 
Test Code:
090-10-0350-04

Order Name:
Lupus Anticoagulant

 
Collection Specimen Or Container:
Blood/ Citrate Blood 3 mL, 2 tubes
 
Specimen Testing Type:
Citrate plasma (immidietely remove plasma after double centrifugation), minimum volume 0.5 mL
 
Sub Mission Container:
Plastic tube
 
Rejection Criteria:
Hemolysis: Hemoglobin >200 mg/dL will be reject.
Lipemia: Triglyceride >500 mg/dL will be reject.
Icterus: Bilirubin >10 mg/dL will be reject.
Other: Clotted specimen will be rejected.
 
Specimen Stabillity:
Specimen Type Temperature Time
Whole blood, Sodium citrate Room temperature, 18oC to 25oC 4 hours
Plasma, Sodium citrate Room temperature, 18oC to 25oC 4 hours
Refrigerated, 2oC to 8oC 4 hours
Frozen, -20oC 2 weeks
Frozen, -70oC 1 year
 
 
 
Test Code:
090-10-0350-04

Order Name:
Lupus Anticoagulant

 
Method detail:
Silica Clotting Time (SCT)
Diluted Russell’s Viper Venom test
 
Schedule:
Tested every Tuesday and Friday at 13:00
Note: If not delivered at the time of testing, will be done in the next round
 
Turnaround Time:
Received specimen to report within 4 days
 
Performing Location:
Hematology, Laboratory Department Tel. 17254
 
Specimen Retention Time:
14 days
 
 
 
Test Code:
090-10-0350-04

Order Name:
Lupus Anticoagulant

 
 
Clinical Information:
Lupus anticoagulants (LA) belong to the group of antiphospholipid antibodies which are directed againts negatively charged phospholipids or complexes between phospholipids and proteins (for example, beta-2-glycoprotein 1 or clotting factors such as prothombin) When determined by their ability to prolong phospholipid-dependent tests (APTT,KCT, DRVVT,SCT) these antibodies are referred to as LA. Patients with LA are at increased risk of clinical complications such as thrombosis and recurrent miscarriages.
 
Reference Value:
Negative
 
Clinical Reference:
  1. Manufacturer’s reagent Package Insert, Silica Clotting Time HemosIL®, Instrumentation Laboratory Company - Bedford, MA 01730-2443 (USA), Instrumentation Laboratory SpA - V.le Monza 338 - 20128 Milano (Italy), 11/2016
  2. Manufacturer’s reagent Package Insert, dRVVT Screen-0020301500/ dRVVT Confirm-0020301600 HemosIL®, Instrumentation Laboratory Company - Bedford, MA 01730-2443 (USA), Instrumentation Laboratory SpA - V.le Monza 338 - 20128 Milano (Italy), 11/2016
  3. http://www.mayomedicallaboratories.com (Retrieved: 22 Jan 2019)