bih.button.backtotop.text
BROWSE BY TEST NAME
%
1
2
3
5
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Clear
 
Test Code:
LI

Order Name:
Lithium

 
Useful For:
Monitoring therapy of patients with bipolar disorders, including recurrent episodes of mania and depression Evaluating lithium toxicity
 
Methodology:
Colorimetric
 
AliasesName:
Li (Lithium)
 
 
 
Test Code:
LI

Order Name:
Lithium

 
Patient Preparation:
Follow the instruction of physician and pharmarcist.
 
Collection Specimen Or Container:
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 0.5 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject 
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20o 6 months
 
 
 
Test Code:
LI

Order Name:
Lithium

 
Method detail:
Colorimetric
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
LI

Order Name:
Lithium

 
 
Clinical Information:
Lithium is used in the treatment of manic depressive psychosis. Lithium acts on the neurotransmitters and produces a sedative effect on the central nervous system. Elevated lithium levels can cause toxicity. Early symptoms of toxicity include apathy, sluggishness, drowsiness, lethargy, speech difficulties, tremor, muscle weakness, and ataxia. Long-term lithium therapy has been reported to cause hyperparathyroidism in some individuals, with resulting hypercalcemia.
 
Reference Value:
Trough level: 0.8 – 1.2 mmol/L
 
Interpretation:
The therapeutic range for lithium has been established at 0.5 to 1.2 mmol/L. Within this range, most people will respond to the drug without symptoms of toxicity. However, response and side effects are individual. Lithium concentrations and side effects can increase with the loss of salt and water from the body, which can occur with a salt-free diet, excessive sweating, or an illness that causes vomiting and diarrhea. A variety of prescribed drugs, over-the-counter medications, and supplements can also increase, decrease, or interfere with the concentrations of lithium.
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, Architect® Lithium, SENTINEL CH. SpAVia Robert Koch 2 Milan 20152, Italy, May 2016.
  2. http://www.uptodate.com (Retrieved: July 2018)
  3. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)