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Test Code:
LACT

Order Name:
Lactate

 
Useful For:
Diagnosing and monitoring patients with lactic acidosis
 
Methodology:
Lactic Acid to Pyruvate
 
AliasesName:
L-Lactate, Blood
Lactic Acid (L-lactate)
 
 
 
Test Code:
LACT

Order Name:
Lactate

 
Patient Preparation:
  1. Patients should not clench and unclench hands before or during phlebotomy. Ideally, a tourniquet should not be used.
  2. Paitent should not be arm flexion before blood collection.
 
Collection Specimen Or Container:
Blood/ NaF blood (Gray Top) 3 mL, 1 tube
 
Specimen Testing Type:
Plasma, minimum volume 0.5 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject 
 
Specimen Stabillity:
Specimen Type Temperature Time
NaF Plasma Refrigerated, 2oC to 8oC 3 days
Frozen, -20o 3 days
 
 
 
Test Code:
LACT

Order Name:
Lactate

 
Method detail:
Lactic Acid to Pyruvate
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
LACT

Order Name:
Lactate

 
 
Clinical Information:
Anaerobic glycolysis markedly increases blood lactate and causes some increase in pyruvate levels, especially with prolonged exercise. The common cause for increased blood lactate and pyruvate is anoxia resulting from such conditions as shock, pneumonia, and congestive heart failure. Lactic acidosis may also occur in renal failure and leukemia. Thiamine deficiency and diabetic ketoacidosis are associated with increased levels of lactate and pyruvate. Lactate measurements that evaluate the acid-base status are used in the diagnosis and treatment of lactic acidosis (abnormally high acidity in the blood).
 
Reference Value:
0.5 – 2.2 mmol/L
 
Interpretation:
While no definitive concentration of lactate has been established for the diagnosis of lactic acidosis, lactate concentrations exceeding 5 mmol/L and pH below 7.25 are generally considered indicative of significant lactic acidosis.
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, ArchitectLactic acid, Fisher Diagnostics,8365 Valley Pike Middletown, VA 22645, USA , January 2016.
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)