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Test Code (รหัสการทดสอบ):
HBOP

Order Name (ชื่อการทดสอบ):
Hemoglobin Typing

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ K3 EDTA (K3E) (Lavender Top) 3 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Received specimen to report within 1 day
 
Useful For (ประโยชน์การทดสอบ):
Diagnosis and comprehensive classification of thalassemias 
 
Methodology (วิธีการทดสอบ):
Capillary Electrophoresis (CE)
 
AliasesName (ชื่อเรียกอื่นๆ) :
Hemoglobin Electrophoresis
 
 
 
Test Code (รหัสการทดสอบ):
HBOP

Order Name (ชื่อการทดสอบ):
Hemoglobin Typing

 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ K3 EDTA (K3E) (Lavender Top) 3 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Blood, minimum volume 0.5 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Original tube
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Whole blood, EDTA Refrigerated, 2oC to 8oC 2 days
 
 
 
Test Code (รหัสการทดสอบ):
HBOP

Order Name (ชื่อการทดสอบ):
Hemoglobin Typing

 
Method detail (วิธีการทดสอบ):
Capillary Electrophoresis (CE)
 
Schedule (ตารางการทดสอบ):
Tested Daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Received specimen to report within 1 day
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Hematology, Laboratory Department Tel. 17254
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
HBOP

Order Name (ชื่อการทดสอบ):
Hemoglobin Typing

 
 
Clinical Information (ข้อมูลทางคลินิก):
This consultative study has the ability to test for the detection of almost all known hemoglobin disorders in an economical manner. Because this can include multiple tests for alpha-thalassemias, beta-thalassemias, delta-beta-thalassemia, hereditary persistence of fetal hemoglobin (HPFH) and for all known Hb variants, an expert in these disorders can guide testing to explain the clinical question or CBC values. This evaluation is particularly useful for complete classification of compound combinations of Hb S with alpha- or beta-thalassemia, Hb E/beta-0-thalassemia, and many other complex thalassemic disorders. Since iron deficiency can mimic thalassemias, ferritin levels are measured to evaluate this possibility. The thalassemias are a group of disorders of hemoglobin (Hb) synthesis. Normal adult Hb consists of 2 alpha globin chains (encoded by 2 pairs of alpha globin genes, each pair located on chromosome 16), and 2 beta globin chains (encoded by 2 beta globin genes, each located on chromosome 11). Thalassemia syndromes result from an underproduction of 1 or 2 types of globin chains and are characterized by the type (alpha, beta, delta) and magnitude of underproduction (number of defective genes) and the severity of clinical symptoms (minor, intermedia, major). The severity of the clinical and hematologic effects is directly related to the imbalance of alpha-like to beta-like chains. The most common form of thalassemia is alpha thalassemia. Hemoglobin H (Hb H) disease, results from dysfunction of 3 alpha chains, and shows a variable phenotype with most showing moderate anemia.
 
Clinical Reference (เอกสารอ้างอิง):
http://www.mayomedicallaboratories.com (Retrieved: 22 Jan 2019)