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Clear
 
Test Code:
090-10-0160-01

Order Name:
Heinz Bodies

 
Useful For:
Test for hemolytic disorders associated with Heinz body formation (eg, G6PD deficiency, thalassemia, unstable hemoglobin)
 
Methodology:
Staining
 
 
 
Test Code:
090-10-0160-01

Order Name:
Heinz Bodies

 
Collection Specimen Or Container:
Blood/ K3 EDTA (K3E) (Lavender Top) 3 mL, 1 tube
 
Specimen Testing Type:
Blood, minimum volume 0.5 mL
 
Sub Mission Container:
Original tube
 
Specimen Stabillity:
Specimen Type Temperature Time
Whole blood, EDTA Refrigerated, 2oC to 8oC 24 hours
 
 
 
Test Code:
090-10-0160-01

Order Name:
Heinz Bodies

 
Method detail:
Staining
 
Schedule:
Tested Daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 5 hours.
 
Performing Location:
Hematology, Laboratory Department Tel. 17254
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
090-10-0160-01

Order Name:
Heinz Bodies

 
 
Clinical Information:
Heinz bodies (HBs) are uncommon except with G6PD deficiency immediately following hemolysis, postsplenectomy, and in patients with unstable hemoglobin variants. They are present characteristically in the congenital Heinz body hemolytic anemias (CHBHA - the unstable hemoglobinopathies). There are now some 200 different identified molecular variants of hemoglobin underlying CHBHA. Less than one-half of these are of clinical significance. The three major causes for HB formation and increased hemolysis are exposure to certain chemicals and drugs, deficiency of one of the reducing systems of blood, and presence of an unstable hemoglobin. Oxidative denaturation of the hemoglobin molecule leads to HB formation with the first two situations and is probably the mechanism for the precipitation of unstable hemoglobin.
 
Reference Value:
No Heinz bodies seen
 
Clinical Reference:
  1. Manufacturer’s reagent package insert Reticulocyte Stain, Baso Biotech Co, Ltd., No.23, Ln.56, Sec.1, Zhonghua Rd., Tucheng Dist., New Taipei City 23666, Taiwan (R.O.C)
  2. http://online.lexi.com (Retrieved: 22 Jan 2019)