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Clear
 
Test Code:
090-71-5022

Order Name:
HLA-B51 **

 
Useful For:
A specific variant of the human leukocyte antigen B51. HLA-B51 is associated with several diseases, including Behçet's disease.
 
Methodology:
Polymerase chain reaction
 
AliasesName:
HLA-B 51
B51 Histocompatibility Antigen
Human Leukocyte Antigen
HLA B*51
 
 
 
Test Code:
090-71-5022

Order Name:
HLA-B51 **

 
Collection Specimen Or Container:
Blood/ K3 EDTA (Lavender Top) 3 mL, 1 tube
 
Specimen Testing Type:
Whole Blood EDTA, minimum volume 3 mL
 
Sub Mission Container:
Original tube
 
Rejection Criteria:
Hemolysis: Hemolysis interfere
Other: Over Stability / Frozen specimen will be reject.
 
Specimen Stabillity:
Specimen Type Temperature Time
Whole blood, EDTA Ambient (preferred) Same day
Refrigerated, 2oC to 8oC 7 days
 
 
 
Test Code:
090-71-5022

Order Name:
HLA-B51 **

 
Method detail:
Polymerase chain reaction
 
Schedule:
N/A **Sent Out to Ramathibodi
 
Turnaround Time:
Reported within 3-5 days (exception for official holidays)
 
Performing Location:
Ramathibodi
Referral Lab Services, Laboratory Department 14160-2
 
 
 
Test Code:
090-71-5022

Order Name:
HLA-B51 **

 
 
Clinical Information:
Testing for HLA-B51 is a useful, though not a diagnostic tool for Behcet's as the vast majority of HLA-B51 carriers do not develop Behcet's. Diagnosis is instead based on the recurrence of symptoms including oral ulcers, genital ulcers, skin lesions and ocular lesions.

The disease is frequently associated with HLA-B51 in the Silk Route countries, up to 80% in Asian patients and 55% in Japan. Japanese carriers of HLA-B51 have a relative risk of 6.7 for Behçet's but only a 1.3 risk in the United States 
 
Reference Value:
Negative
 
Interpretation:
HLA-B51 Positive result adds weight to a clinical diagnosis of Behcet's disease. Ethical may also considerations. This is a not a diagnostic test and the result does not prove or exclude a specific clinical diagnosis in an affected person. 
 
 
Clinical Reference:
www.mayoclinic.org/diseases-conditions/behcets-disease (Retrieved: 20 May 2020)
www.sciencedirect.com/topics/medicine-and-dentistry/hla-b51-antigen (Retrieved: 20 May 2020)