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Test Code:
094-50-0001

Order Name:
HER2, DISH

 
Useful For:
To figure out if breast cancer cells from immunohistochemical stain are HER2-positive.
 
Methodology:
Dual in situ hybridization (DISH)
 
 
 
Test Code:
094-50-0001

Order Name:
HER2, DISH

 
Collection Specimen Or Container:
1. Tissue in 10% neutral buffered formalin or 
2. Paraffin embedded tissue block or
3. Unstained positively charged slides as least 2 slides
 
Specimen Testing Type:
1. Tissue in 10% neutral buffered formalin or 
2. Paraffin embedded tissue block or
3. Unstained positively charged slides as least 2 slides
 
Sub Mission Container:
1. Tissue in 10% neutral buffered formalin or 
2. Paraffin embedded tissue block or
3. Unstained positively charged slides as least 2 slides
 
Rejection Criteria:
Wet/ frozen tissue
Cytology smears
Non formalin fixed tissue  
Non paraffin embedded tissue
Non charged slides
 
Specimen Stabillity:
 
Specimen Type Temperature
Tissue 1. Room temperature for Tissue in  10% neutral buffered formalin (Breast tissue should be fixed in formalin for 6-48 hours, not to exceed 72 hours )
2. Room temperature for paraffin embedded tissue block and unstained slide
 
 
 
Test Code:
094-50-0001

Order Name:
HER2, DISH

 
Schedule:
Tested daily, at 07:00 am. -  06:00 pm.
 
Turnaround Time:
5 days
 
Performing Location:
Surgical Pathology, Laboratory Department,
Tel.14146
 
Specimen Retention Time:
10 years after final report
 
 
 
Test Code:
094-50-0001

Order Name:
HER2, DISH

 
 
Clinical Information:
HER2-positive breast cancers make too much of the HER2 protein, which receives signals telling the breast cancer to grow. About one out of every four breast cancers is HER2-positive. Figuring out the HER2 status of a breast cancer is an important step in deciding on a treatment plan. The targeted therapy medicines Herceptin (chemical name: trastuzumab) and Tykerb (chemical name: lapatinib) are used to treat HER2-positive breast cancers.
 
Clinical Reference:
1.https://www.breastcancer.org/symptoms/testing/types/inform_her2_dual_ish (Retrieved: 1 Feb 19)