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Clear
 
Test Code (รหัสการทดสอบ):
090-31-4015

Order Name (ชื่อการทดสอบ):
Complement C1q, Serum **

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 5 mL, 1 tube 


 
 
Turnaround Time (ระยะเวลารอผล):
Received specimen to reported within 14 days
 
 
Useful For (ประโยชน์การทดสอบ):

1. Assessment of an undetectable total complement (CH50) level.
2. Diagnosing congenital C1 (first component of complement) deficiency.
3. Diagnosing acquired deficiency of C1 inhibitor.

 
Methodology (วิธีการทดสอบ):
Nephelometry
 
AliasesName (ชื่อเรียกอื่นๆ) :
C1Q (Complement Component C1Q), Serum
Complement Component C1q
First Component of Complement
 
 
 
Test Code (รหัสการทดสอบ):
090-31-4015

Order Name (ชื่อการทดสอบ):
Complement C1q, Serum **

 
Patient Preparation (การเตรียมตัวผู้ป่วย):
Patient must be fasting 8-12 hours.
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain Blood (Red Top) 5 mL, 1 tube 


 
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 2-3 mL (Ship Frozen)
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic tube
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Lipemic :4+ reject 

 
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen 28 days
  Ambient  21 days

 
 
 
 
Test Code (รหัสการทดสอบ):
090-31-4015

Order Name (ชื่อการทดสอบ):
Complement C1q, Serum **

 
Method detail (วิธีการทดสอบ):
Nephelometry
 
Schedule (ตารางการทดสอบ):
N/A **Sent out to MAYO, USA
 
Turnaround Time (ระยะเวลารอผล):
Received specimen to reported within 14 days
 
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
MAYO Laboratory
Referral Lab Services, Laboratory Department 14160-2
 
 
 
Test Code (รหัสการทดสอบ):
090-31-4015

Order Name (ชื่อการทดสอบ):
Complement C1q, Serum **

 
 
Clinical Information (ข้อมูลทางคลินิก):

The first component of complement (C1) is composed of 3 subunits designated as C1q, C1r, and C1s. C1q recognizes and binds to immunoglobulin complexed to antigen and initiates the complement cascade. Congenital deficiencies of any of the early complement components (C1, C2, C4) results in an inability to clear immune complexes. Inherited deficiency of C1 is rare.
Like the more common C2 deficiency, C1 deficiency is associated with increased incidence of immune complex disease (systemic lupus erythematosus, polymyositis, glomerulonephritis, and Henoch-Schonlein purpura). Low C1 levels have also been reported in patients with abnormal immunoglobulin levels (Bruton and common variable hypogammaglobulinemia and severe combined immunodeficiency). This is most likely due to increased catabolism.
The measurement of C1q is an indicator of the amount of C1 present.

 
Reference Value (ค่าอ้างอิง):
12-22 mg/dL
 
Interpretation (การแปลผล):

An undetectable C1q in the presence of an absent total complement (CH50) and normal C2, C3, and C4 suggests a congenital C1 (first component of complement) deficiency.
A low C1q in combination with a low C1 inhibitor and low C4 suggests an acquired C1 inhibitor deficiency.

 
Clinical Reference (เอกสารอ้างอิง):
www.mayomedicallaboratories.com (Retrieved: 25 Jun 2020)