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Test Code:
090-10-0200-01

Order Name:
Clotting Time

 
Useful For:
Venomous snakebites contribute to morbidity and mortality throughout the world, most commonly in resource-poor areas, with about 2.5 million humans sustaining snakebites annually. Coagulopathy is a significant cause of both morbidity and mortality in these patients. In the absence of more sophisticated hematological studies or obvious physical findings, many clinicians must rely on whole-blood clotting times to assess whether their patients are coagulopathic.
 
Methodology:
20 minute whole blood clotting test (20WBCT)
 
AliasesName:
20WBCT
 
 
 
Test Code:
090-10-0200-01

Order Name:
Clotting Time

 
Collection Specimen Or Container:
Blood/ Glass test tube
 
Specimen Testing Type:
Whole blood/ Bedside testing
 
 
 
Test Code:
090-10-0200-01

Order Name:
Clotting Time

 
Method detail:
20 minute whole blood clotting test (20WBCT)
 
Schedule:
Tested Daily (24 hours)
 
Turnaround Time:
Collected specimen to reported within 45 mins.
 
Performing Location:
Hematology, Laboratory Department Tel. 17254
 
 
 
Test Code:
090-10-0200-01

Order Name:
Clotting Time

 
 
Clinical Information:
The 20-minute whole blood clotting test (WBCT20) is used as a bedside diagnostic test for coagulopathic snake envenoming. We aimed to assess the performance of the WBCT20 in diagnosis of venom induced consumption coagulopathy (VICC) in Russell's viper envenoming. 

In order for blood to clot, the enzyme thrombin must be generated from the plasma precursor prothrombin. Thrombin then converts soluble fibrinogen into insoluble fibrin. Generation of thrombin involves the sequential activation of a number of other plasma clotting factor, this process is also being assisted by Ca++ and by factors released by platelets and damaged tissues . The time taken for blood to clot mainly reflects the time required for the generation of thrombin in this manner. If the plasma concentration of prothrombin or of some of the other factors is low (or if the factor is absent, or functionally inactive), clotting time will be prolonged. The expected range for clotting time is less than 20 mins.
 
Reference Value:
<20 mins
 
Clinical Reference:
  1. WHO (Supplement to the Southeast Asian Journal of Tropical Medicine and Public Health Volume 30 Supplement 1, 1999)
  2. https://www.medicine.mcgill.ca/physio/vlab/bloodlab/hemostasis_n.htm