Test Code (รหัสการทดสอบ):
Order Name (ชื่อการทดสอบ):
CRP (C-Reactive Protein), High Sensitivity
Clinical Information (ข้อมูลทางคลินิก):
C-reactive protein (CRP) is an acute phase protein whose concentration rises non-specifically in response to inflammation. CRP is seen to increase as a result of the inflammatory process, most notably in response to pneumococcal (bacterial) infection, histolytic disease, and a variety of other disease states. Intraindividual variation is a major limitation of the assay when the assay is used for directing therapies. Intraindividual variations of the CRP levels are from 30% to 60%. Serial measurement may be required to estimate true mean of CRP depending on the intended use in any specific individual. CRP is used as a marker or general diagnostic indicator of infections and inflammation, in addition to serving as a monitor of patient response to pharmacological therapy and surgery.
Reference Value (ค่าอ้างอิง):
≤ 0.5 mg/dL
For Coronary vascular disease risk assessment according to AHA/CDC recommendation see the table below
| Reference value (mg/dL)
|| Risk assessment
|0.1 - 0.3
Elevated values are consistent with an acute inflammatory process. After onset of an acute phase response, the serum CRP concentration rises rapidly (within 6-12 hours and peaks at 24-48 hours) and extensively. Concentrations above 100 mg/L are associated with severe stimuli such as major trauma and severe infection (sepsis).
Clinical Reference (เอกสารอ้างอิง):
- Manufacturer’s reagent package insert, Architect® CRP Vario, SENTINEL CH. SpA Via Robert Koch, 2 Milan 20125, Italy .
- http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)