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Clear
 
Test Code:
090-10-1045-01

Order Name:
%CD16/56

 
Useful For:
Useful for follow-up and diagnostic evaluation of primary cellular immunodeficiencies, including severe combined immunodeficiency.

T-cell immune monitoring following immunosuppressive therapy for transplantation, autoimmunity, and other immunological conditions where such treatment is utilized.

Assessment of T-cell immune reconstitution post hematopoietic cell transplantation.

Early screening of gross quantitative anomalies in T cells in infection or malignancies.
 
Methodology:
Flow cytometry
 
Test List In Profile:
WBC count
% Lymphocyte
CD3 Cell Count
% CD3
% CD16/56
 
AliasesName:
NK cell
 
 
 
Test Code:
090-10-1045-01

Order Name:
%CD16/56

 
Collection Specimen Or Container:
Blood/ K3 EDTA (K3E) (Lavender Top) 3 mL, 1 tube
 
Specimen Testing Type:
Blood, minimum volume 2 mL
 
Sub Mission Container:
Original tube
 
Rejection Criteria:
Clotted specimen will be rejected.
 
Specimen Stabillity:
Specimen Type Temperature Time
Blood  Refrigerated, 18oC to 24oC 24 hours
 
 
 
Test Code:
090-10-1045-01

Order Name:
%CD16/56

 
Method detail:
Flow cytometry
 
Schedule:
Tested Daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1 day.
 
Performing Location:
Hematology, Laboratory Department Tel. 17254
 
 
 
Test Code:
090-10-1045-01

Order Name:
%CD16/56

 
 
Clinical Information:
Abnormalities in the number and percent of T (CD3, CD4, CD8), B (CD19), and NK (CD16+CD56) lymphocytes have been described in a number of different disease conditions. In patients who are infected with HIV, the CD4 count is measured for AIDS diagnosis and for initiation of antiviral therapy. The progressive loss of CD4 T-lymphocytes inpatients infected with HIV is associated with increased infections and complications. The Public Health Service has recommended that all HIV-positive patients be tested every 3 to 6 months for the level of CD4 T lymphocytes.

Lymphocyte subset quantitation is also very useful in the evaluation of patients with primary immunodeficiencies of all ages, including follow-up for newborn screening for severe combined immunodeficiency (SCID) and immune monitoring following immunosuppressive therapy for transplantation, autoimmunity, or any other relevant clinical condition where immunomodulatory treatment is used.

It is also helpful as a preliminary screening assay for gross quantitative anomalies in any lymphocyte subset, whether related to malignancies or infection.
 
Reference Value:
6.0 - 29.0
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, IOTest® CD3-FITC/CD (16+56)-PE A08835 2012-06-01_GB.  Beckman Coulter, Inc. U.S.A. 12/2016
  2. http://www.mayomedicallaboratories.com (Retrieved: 22 Jan 2019)