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Clear
 
Test Code:
CRP

Order Name:
C-Reactive Protein (CRP)

 
Useful For:
  1. Detecting systemic inflammatory processes
  2. Detecting infection and assessing response to antibiotic treatment of bacterial infection
       Differentiating between active and inactive disease forms with concurrent infection
 
Methodology:
Turbidimetric/ Immunoturbidimetric
 
AliasesName:
CRP
Protein, C-Reactive
hsCRP
High Sensitivity C-reactive Protein 
 
 
 
Test Code:
CRP

Order Name:
C-Reactive Protein (CRP)

 
Collection Specimen Or Container:
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 0.5 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject 
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 3 months
Frozen, -20o 12 months
 
 
 
Test Code:
CRP

Order Name:
C-Reactive Protein (CRP)

 
Method detail:
Turbidimetric/ Immunoturbidimetric
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
CRP

Order Name:
C-Reactive Protein (CRP)

 
 
Clinical Information:
C-reactive protein (CRP) is an acute phase protein whose concentration rises non-specifically in response to inflammation. CRP is seen to increase as a result of the inflammatory process, most notably in response to pneumococcal (bacterial) infection, histolytic disease, and a variety of other disease states. Intraindividual variation is a major limitation of the assay when the assay is used for directing therapies. Intraindividual variations of the CRP levels are from 30% to 60%. Serial measurement may be required to estimate true mean of CRP depending on the intended use in any specific individual. CRP is used as a marker or general diagnostic indicator of infections and inflammation, in addition to serving as a monitor of patient response to pharmacological therapy and surgery.
 
Reference Value:
≤ 0.5 mg/dL
 
Interpretation:
Elevated values are consistent with an acute inflammatory process. After onset of an acute phase response, the serum CRP concentration rises rapidly (within 6-12 hours and peaks at 24-48 hours) and extensively. Concentrations above 100 mg/L are associated with severe stimuli such as major trauma and severe infection (sepsis).
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, Architect® CRP Vario, SENTINEL CH. SpA Via Robert Koch, 2 Milan 20125, Italy, August 2015.
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)