Adenoviruses were described as latent persisting agents in tonsils and adenoid tissue, as well as the cause of acute respiratory tract infection. Human adenoviruses cause a variety of diseases including pneumonia, cystitis, conjunctivitis, diarrhea, hepatitis, myocarditis, and encephalitis. Infections can occur at any time of the year and in all age groups. Currently, there are 51 adenovirus serotypes that have been grouped into 6 separate subgenera.
Serotype 1-8, 40, and 41 are most commonly isolated from humans.