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Test Code (รหัสการทดสอบ):
ACE

Order Name (ชื่อการทดสอบ):
ACE (Angiotensin Converting Enzyme), Blood **

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 2 tubes
 
Turnaround Time (ระยะเวลารอผล):
Received specimen to report within 14 days
 
Useful For (ประโยชน์การทดสอบ):
Evaluation of patients with suspected sarcoidosis
 
Methodology (วิธีการทดสอบ):
Spectrophotometry (SP)
 
AliasesName (ชื่อเรียกอื่นๆ) :
ACE (Angiotensin Converting Enzyme) Angiotensin-1-Converting Enzyme Kinase II Peptidylpeptide Hydrolase SACE (Serum Angiotensin Convert
Angiotensin-1-Converting Enzyme
Kinase II
Peptidylpeptide Hydrolase
SACE (Serum Angiotensin Converting Enzyme)
Sarcoidosis
Serum Angiotensin Converting Enzyme
ACE (Angiotensin Converting Enzyme)
 
 
 
Test Code (รหัสการทดสอบ):
ACE

Order Name (ชื่อการทดสอบ):
ACE (Angiotensin Converting Enzyme), Blood **

 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 2 tubes
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 2 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic tube
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Hemolysis: Mild reject; Gross reject
Lipemia: Mild OK; Gross reject
Icterus: Mild reject; Gross reject
Other: N/A
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum Ambient 24 hours
Serum Refrigerated, 2oC to 8oC (preferred) 7 days
Serum Frozen 180 days
 
 
 
Test Code (รหัสการทดสอบ):
ACE

Order Name (ชื่อการทดสอบ):
ACE (Angiotensin Converting Enzyme), Blood **

 
Method detail (วิธีการทดสอบ):
Spectrophotometry (SP)
 
Schedule (ตารางการทดสอบ):
N/A **Sent out to MAYO, USA
 
Turnaround Time (ระยะเวลารอผล):
Received specimen to report within 14 days
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
MAYO Laboratory
Referral Lab Services, Laboratory Department 14160-2
 
 
 
Test Code (รหัสการทดสอบ):
ACE

Order Name (ชื่อการทดสอบ):
ACE (Angiotensin Converting Enzyme), Blood **

 
 
Clinical Information (ข้อมูลทางคลินิก):
Angiotensin converting enzyme (ACE) participates in the renin cascade in response to hypovolemia. Its peptidase action on the decapeptide angiotensinogen I results in the hydrolysis of a terminal histidyl leucine dipeptide and the formation of the octapeptide angiotensin II, a potent vasoconstrictor that increases blood pressure.
 
Reference Value (ค่าอ้างอิง):

> or =18 years: 16-85 U/L

0-17 years: ACE activity may be 20-50% higher in healthy children compared to healthy adults (16-85 U/L).

Necessary Information
The use of angiotensin converting enzyme (ACE)-inhibiting antihypertensive drugs will cause decreased ACE values. Patients taking ACE inhibitors, such as captopril and enalapril, will have extremely low or unmeasurable ACE activity. 

 

 
Interpretation (การแปลผล):
An elevation in the level of serum angiotensin converting enzyme (ACE), along with radiographic evidence of infiltrates or adenopathy and organ biopsies showing noncaseating epithelial granulomas is suggestive of a diagnosis of sarcoidosis.

Serum ACE is significantly higher in most (approximately 80%) patients with active sarcoidosis. ACE is also elevated in a number of other diseases and in approximately 5% of the normal adult population.
 
Clinical Reference (เอกสารอ้างอิง):
www.mayomedicallaboratories.com (Retrieved: 24 Jan 2019)