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Test Code:
090-20-0461-01

Order Name:
2 hrs. GTT, DEX 75 g. ( Draw blood at 2 hrs. only)

 
Useful For:
Diagnosis and screening for diabetes or prediabetes.
 
Methodology:
Hexokinase/ G-6-PDH
 
AliasesName:
Glucose Tolerance Test
Oral Glucose Tolerance Test (OGTT)
Sugar
 
 
 
Test Code:
090-20-0461-01

Order Name:
2 hrs. GTT, DEX 75 g. ( Draw blood at 2 hrs. only)

 
Patient Preparation:
Patient should be fasting at least 8 hours.
 
Collection Specimen Or Container:
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 0.5 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject

 
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20oC 1 month
 
 
 
Test Code:
090-20-0461-01

Order Name:
2 hrs. GTT, DEX 75 g. ( Draw blood at 2 hrs. only)

 
Method detail:
Hexokinase/ G-6-PDH
 
Schedule:
Tested daily (24 Hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
090-20-0461-01

Order Name:
2 hrs. GTT, DEX 75 g. ( Draw blood at 2 hrs. only)

 
 
Clinical Information:
The OGTT evaluates how the body manages glucose after a meal. Glucose is a type of sugar produced when the body breaks down carbohydrates consumed in food. Some of the glucose will be used for energy; the rest will be stored for future use.

The amount of glucose in your blood is controlled by the hormones insulin and glucagon. If you have too much, the pancreas secretes insulin to help cells absorb and store glucose. If you have too little, the pancreas secretes glucagon so that stored glucose can be released back into the bloodstream.

Under normal circumstances, the body will be able to maintain the ideal balance of blood glucose. However, if any parts of the system are impaired, glucose can rapidly accumulate, leading to high blood sugar (hyperglycemia) and diabetes.

The OGTT is a highly sensitive test that can detect imbalances that other tests miss. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) recommends the OGTT for the following purposes:
- Screening and diagnosis of prediabetes or impaired glucose tolerance (IGT)
- Screening and diagnosis of type 2 diabetes.
- Screening and diagnosis of gestational diabetes.

The OGTT is only used for diagnosis and screening. It has no role in the monitoring of diabetes or prediabetes.

Among its other uses, the OGTT can be ordered to diagnose reactive hypoglycemia (in which blood sugar drops after eating), acromegaly (an overactive pituitary gland), beta cell dysfunction (in which insulin is not being secreted), and rare disorders affecting carbohydrate metabolism (such as hereditary fructose intolerance).
 
Reference Value:
Oral Glucose Tolerance Test (OGTT)
Levels applicable except during pregnancy.  Sample drawn 2 hours after a 75-gram glucose drink.
 
Glucose Level Indication
Less than 140 mg/dL (7.8 mmol/L) Normal glucose tolerance
From 140 to 199 mg/dL (7.8 to 11.11 mmol/L) Impaired glucose tolerance (pre-diabetes)
200 mg/dL (11.1 mmol/L) and above on more than
one testing occasion
Consider diagnostic for diabetes
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, Architect® Glucose Abbott Laboratories, Abbott Park IL 60064 USA, October 2012.
  2. http://www.diabetes.org/diabetes-basics/diagnosis (Retrieved: June 2018)
  3. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)
  4. https://www.verywellhealth.com (Retrieved: 9 Mar 2019)