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Clear
 
Test Code:
090-10-0100-01

Order Name:
VDRL

 
Useful For:
Determining the current disease status and evaluating response to therapy for syphilis
 
Methodology:
Flocculation
 
AliasesName:
Rapid Plasma Reagin Test (RPR)
Syphilis G
Treponema pallidum (T. pallidum)
Syphilis Serology (RPR)
 
 
 
Test Code:
090-10-0100-01

Order Name:
VDRL

 
Collection Specimen Or Container:
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 1 mL
 
Sub Mission Container:
Plastic tube
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 5 days
Frozen, -20oC 5 days
 
 
 
Test Code:
090-10-0100-01

Order Name:
VDRL

 
Method detail:
Flocculation
 
Schedule:
Tested Daily (24 hours)
 
Turnaround Time:
Collected specimen to reported within 90 mins.
 
Performing Location:
Hematology, Laboratory Department Tel. 17254
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
090-10-0100-01

Order Name:
VDRL

 
 
Clinical Information:
Syphilis is a disease caused by infection with the spirochete Treponema pallidum. The infection is systemic and the disease is characterized by periods of latency. These features, together with the fact that T pallidum cannot be isolated in culture, mean that serologic techniques play a major role in the diagnosis and follow-up of treatment for syphilis. Patients with primary or secondary syphilis should be reexamined clinically and serologically 6 months and 12 months following treatment. Typically, rapid plasma reagin titers decrease following successful treatment, but this may occur over a period of months to years.
 
Reference Value:
Non - Reactive
 
Interpretation:
Treatment response is generally indicated by a 4-fold (2-tube dilution) reduction in rapid plasma reagin (RPR) titer (eg, from 1:32 to 1:8). For proper interpretation of RPR results, titers should be obtained using the same testing method and, preferably, at the same testing laboratory. Failure of nontreponemal test titers to decline 4-fold within 6 months after therapy for primary or secondary syphilis may be indicative of treatment failure. Patients whose titers remain serofast should be reevaluated for HIV infection.
 
Clinical Reference:
  1. Manufacturer’s reagent package insert Macro-VueTM RPR Card Tests Becton Dickinson 2015.
  2. http://www.mayomedicallaboratories.com (Retrieved: 22 Jan 2019)