bih.button.backtotop.text
BROWSE BY TEST NAME
%
1
2
3
5
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Clear
 
Test Code:
090-30-2100-01

Order Name:
Phenobarbital  (Blood)

 
Useful For:
Measurement of phenobarbital, an anticonvulsant and sedative-hypnotic drug, in human serum.

The measurements obtained are used in the diagnosis and treatment of phenobarbital overdose and in monitoring levels of phenobarbital to help ensure appropriate therapy.
 
Methodology:
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
 
 
Test Code:
090-30-2100-01

Order Name:
Phenobarbital  (Blood)

 
Collection Specimen Or Container:
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 1 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum (keep in original tube) Room temperature, 20oC to 28oC 8 hours
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20oC 6 months
 
 
 
Test Code:
090-30-2100-01

Order Name:
Phenobarbital  (Blood)

 
Method detail:
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
Schedule:
Tested Daily (24 Hours)
 
Turnaround Time:
Specimen collected to reported within 2:00 Hours (120 Mins)
 
Performing Location:
Immunology, Laboratory Department Tel. 13227
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
090-30-2100-01

Order Name:
Phenobarbital  (Blood)

 
 
Clinical Information:
Phenobarbital was introduced in 1912 for the treatment of epilepsy, particularly for controlling focal motor or sensory seizures and grand mal seizures. Phenobarbital is bound to both plasma and tissue proteins.
Monitoring serum concentrations of phenobarbital has been shown to improve patient therapy by providing physicians with a tool for adjusting dosage.  In addition, because of the narrow therapeutic index and wide inter-individual variability in the rate of phenobarbital metabolism and clearance, the determination of blood levels of phenobarbital for patients receiving therapy is essential.
 
Reference Value:
Trough level: 10 - 40 µg/mL
 
Clinical Reference:
  1. Manufacturer’s Reagent package insert, Architect iPhenobarbital, October 2015, Abbott Laboratories, MAX-  Planck-Ring 65205 Wiesbaden, Germany.
  2. Reference intervals: UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com (Retrieved: July2018)