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Test Code (รหัสการทดสอบ):
090-20-1560-01

Order Name (ชื่อการทดสอบ):
Microalbuminuria* (U-24 hrs)

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
24-hour urine, Clean containner with non preservative

Note:
  • Please keep in refrigerated (2-8°C) during collection and transportation
  • 24-hours volume is required.
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 1.5 hours (90 mins)
 
Useful For (ประโยชน์การทดสอบ):
Evaluating diabetic patients to assess the potential for early onset of nephropathy
 
Methodology (วิธีการทดสอบ):
Turbidimetric/Immunoturbidimetric
 
AliasesName (ชื่อเรียกอื่นๆ) :
Albumin, U-24 hrs.
MAU, U-24 hrs.
 
 
 
Test Code (รหัสการทดสอบ):
090-20-1560-01

Order Name (ชื่อการทดสอบ):
Microalbuminuria* (U-24 hrs)

 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
24-hour urine, Clean containner with non preservative

Note:
  • Please keep in refrigerated (2-8°C) during collection and transportation
  • 24-hours volume is required.
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
24-hour urine, minimum volume 10 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Clean container
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Specimen with preservative type will be reject
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
24-hours urine Refrigerated, 2oC to 8oC 7 days
 
 
 
Test Code (รหัสการทดสอบ):
090-20-1560-01

Order Name (ชื่อการทดสอบ):
Microalbuminuria* (U-24 hrs)

 
Method detail (วิธีการทดสอบ):
Turbidimetric/Immunoturbidimetric
 
Schedule (ตารางการทดสอบ):
Tested daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
7 days
 
 
 
Test Code (รหัสการทดสอบ):
090-20-1560-01

Order Name (ชื่อการทดสอบ):
Microalbuminuria* (U-24 hrs)

 
 
Clinical Information (ข้อมูลทางคลินิก):
Microalbuminuria is a condition characterized by increased urinary excretion of albumin in the absence of overt nephropathy, and can be used to predict diabetic nephropathy. Diabetic nephropathy is a major cause of death in individuals with insulin-dependent diabetes; and because it is accompanied by irreversible kidney damage and persistent proteinuria, it is a major factor in the decision to initiate hemodialysis. 
Early detection of glomerular damage, when it is minimal and reversible, is extremely important. Monitoring urinary microalbumin is an important component of treatment for both Type I and Type II diabetes mellitus.
Methods for monitoring microalbuminuria include measurement of protein excretion in 24 hour, timed, or overnight collections, and determination of the albumin:creatinine ratio in an untimed “spot” urine specimen. Twenty-four hour and timed urine collections may be associated with collection errors including improper timing, missed samples, and incomplete bladder emptying. The concentration of protein in a spot urine sample provides an estimate of the protein excretion rate, but is affected by patient hydration. The ratio of protein or albumin to creatinine in a spot urine sample corrects for variations in hydration and avoids the sources of error associated with 24 hour and timed urine collection.
 
Reference Value (ค่าอ้างอิง):
 <30 mg/24 hrs
 
Interpretation (การแปลผล):
An albumin excretion rate of more than 30 mg/24 hours is considered to be microalbuminuric. By definition, the upper end of microalbuminuria is thought to be 300 mg/24 hours. Although this level has not been rigorously defined, it is felt that at this level it is more difficult to change the course of diabetic nephropathy. We have established normal values in our laboratory and agree with the 30 mg/24 hour level. A normal excretion rate of 20 mcg/minute has also been established in the literature and is consistent with our data. Thus, microalbuminuria has been defined at 30 to 300 mg/24 hours.
 
Clinical Reference (เอกสารอ้างอิง):
  1. Manufacturer’s reagent package insert, Architect® Microalbumin, Wako Pure Chemical Industries, Ltd. 2613-2 Oaza, Ogohara, Komono-cho Mie-gun, Mie 510-1222, Japan, February 2017.
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)