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Test Code:
MGU

Order Name:
Magnesium (Random Urine)

 
Useful For:
  1. Assessing the cause of abnormal serum magnesium concentrations
  2. Determining whether nutritional magnesium loads are adequate
  3. Calculating urinary calcium oxalate and calcium phosphate supersaturation and assessing kidney stone risk.
 
Methodology:
 Arsenazo
 
AliasesName:
Mg (Magnesium), Random urine
 
 
 
Test Code:
MGU

Order Name:
Magnesium (Random Urine)

 
Collection Specimen Or Container:
Urine, Clean container 
 
Specimen Testing Type:
Urine, minimum volume 10 mL
 
Sub Mission Container:
Clean container
 
Specimen Stabillity:
Specimen Type Temperature Time
Random urine Refrigerated, 2oC to 8oC 3 days
Frozen, -20oC 12 months
 
 
 
Test Code:
MGU

Order Name:
Magnesium (Random Urine)

 
Method detail:
 Arsenazo
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
7 days
 
 
 
Test Code:
MGU

Order Name:
Magnesium (Random Urine)

 
 
Clinical Information:
Magnesium is an essential nutrient which is involved in many biochemical functions. It has a structural role in nucleic acids and ribosomal particles, required as an activator for many enzymes and has a role in energy producing oxidative phosphorylation.

The normal body contains between 21 to 28 g magnesium, more than 50% of which is complexed with calcium and phosphate in bone. Only approximately 1% of the total magnesium is found in the extracellular fluid; hence, it tends to enter and leave cells under the same conditions as potassium. Approximately 35% of plasma magnesium is protein-bound, mainly to albumin, and therefore changes in albumin concentration may affect magnesium.

Hypomagnesemia results in the impairment of neuromuscular function and may develop in severe prolonged diarrhea, malabsorption syndromes, hyperaldosteronism, and diuretic therapy. Hypermagnesemia is seen in renal glomerular failure and diabetic coma.
 
Interpretation:
Urinary magnesium excretion should be interpreted in concert with serum concentrations.

In the presence of hypomagnesemia, a 24-hour urine magnesium >24 mg/day or fractional excretion >0.5% suggests renal magnesium wasting. Lower values suggest inadequate magnesium intake and/or gastrointestinal losses.

In the presence of hypermagnesemia, urinary magnesium levels provide an indication of current magnesium intake.

Lower urinary magnesium excretion increases urinary calcium oxalate and calcium phosphate supersaturation and could contribute to kidney stone risk.
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, Architect® Magnesium, Abbott Laboratories, Abbott Park IL 60064 USA, March 2015.
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)