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Clear
Overview
ข้อมูลทั่วไป Specimen
ข้อมูลสิ่งส่งตรวจ Performance
ข้อมูลการทดสอบ Clinical & Interpretation
ข้อมูลทางคลินิก
 
Test Code (รหัสการทดสอบ):
090-71-5520
Order Name (ชื่อการทดสอบ):
INVITAE Multi-Cancer Panel 84 genes (Diagnostic test) **
 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ K3 EDTA (Lavender Top) 6 mL, 1 tube

Document Required:
Completed Requesition Form (Select Multi-Cancer Panel)
& Completed Consent Form
 
Turnaround Time (ระยะเวลารอผล):
30 days
 
Useful For (ประโยชน์การทดสอบ):

This panel may be considered for individuals with:

  • a personal or family history presenting with multiple cancer types that could fit the features of more than one hereditary cancer syndrome
  • a clinical history indicative of a hereditary cancer syndrome but a limited pedigree due to small family size or adoption

There are also some common general features suggestive of a family with a hereditary cancer syndrome. These include:

  • cancer diagnosed at an unusually young age
  • different types of cancer that have occurred independently in the same person
  • cancer that has developed in both organs of a set of paired organs (e.g., both kidneys, both breasts)
  • several close blood relatives that have the same type of cancer
  • unusual cases of a specific cancer type (e.g., male breast cancer)
 
Methodology (วิธีการทดสอบ):
Next-generation sequencing (NGS)
 
Test List In Profile (การทดสอบใน Profile):

Analyzes 84 genes:
AIP ALK APC ATM AXIN2 BAP1 BARD1 BLM BMPR1A BRCA1 BRCA2 BRIP1 CASR CDC73 CDH1 CDK4 CDKN1B CDKN1C CDKN2A CEBPA CHEK2 CTNNA1 DICER1 DIS3L2 EGFR EPCAM FH FLCN GATA2 GPC3 GREM1 HOXB13 HRAS KIT MAX MEN1 MET MITF MLH1 MSH2 MSH3 MSH6 MUTYH NBN NF1 NF2 NTHL1 PALB2 PDGFRA PHOX2B PMS2 POLD1 POLE POT1 PRKAR1A PTCH1 PTEN RAD50 RAD51C RAD51D RB1 RECQL4 RET RUNX1 SDHA SDHAF2 SDHB SDHC SDHD SMAD4 SMARCA4 SMARCB1 SMARCE1 STK11 SUFU TERC TERT TMEM127 TP53 TSC1 TSC2 VHL WRN WT1

 
AliasesName (ชื่อเรียกอื่นๆ) :
INVITAE 1 Panel Genetic Testing (Diagnostic test) 
 
 
 
Test Code (รหัสการทดสอบ):
090-71-5520
Order Name (ชื่อการทดสอบ):
INVITAE Multi-Cancer Panel 84 genes (Diagnostic test) **
 
Patient Preparation (การเตรียมตัวผู้ป่วย):
Genetics Counseling
 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ K3 EDTA (Lavender Top) 6 mL, 1 tube

Document Required:
Completed Requesition Form (Select Multi-Cancer Panel)
& Completed Consent Form
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Blood/ K3 EDTA (Lavender Top) 6 mL, 1 tube
 
Sub Mission Container (ภาชนะส่งตรวจ):
Whole blood EDTA, minimum volume 6 mL
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
  • Hemolyzed or clotted blood
  • Blood (or saliva) from patients who have had an allogeneic (non-self donor) bone marrow transplant
  • Blood (or saliva) from patients who have had an allogeneic (non-self donor) stem cell transplant
  • Blood (or saliva) from patients who had a blood transfusion less than two weeks prior to specimen collection
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Whole blood EDTA Refrigerated, 2oC to 8oC 14 days
Saliva (2mL) in special collection kit * Ambient 30 days
* Optional, Nurse can request the special collection kit from Lab 4th Floor, Tel. 14160-2​
** Sending to USA
 
 
 
 
Test Code (รหัสการทดสอบ):
090-71-5520
Order Name (ชื่อการทดสอบ):
INVITAE Multi-Cancer Panel 84 genes (Diagnostic test) **
 
Method detail (วิธีการทดสอบ):
Next-generation sequencing (NGS)
 
Schedule (ตารางการทดสอบ):
N/A **Sent out to INVITAE, USA
 
Turnaround Time (ระยะเวลารอผล):
30 days
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
INVITAE, USA
Referral Lab Services, Laboratory Department 14160-2
 
 
 
Test Code (รหัสการทดสอบ):
090-71-5520
Order Name (ชื่อการทดสอบ):
INVITAE Multi-Cancer Panel 84 genes (Diagnostic test) **
 
 
Clinical Information (ข้อมูลทางคลินิก):

The Invitae Multi-Cancer Panel analyzes 84 genes associated with hereditary cancers across major organ systems, including:

  • breast and gynecologic (breast, ovarian, uterine)
  • gastrointestinal (colorectal, gastric, pancreatic)
  • endocrine (thyroid, paraganglioma/pheochromocytoma, parathyroid, pituitary)
  • genitourinary (renal/urinary tract, prostate)
  • skin (melanoma, basal cell carcinoma)
  • brain/nervous system
  • sarcoma
  • hematologic (myelodysplastic syndrome/leukemia)

The Invitae Multi-Cancer Panel is designed to maximize diagnostic yield for individuals with a personal or family history of mixed cancers affecting multiple organ systems.

Genetic testing of these genes may confirm a diagnosis and help guide treatment and management decisions. Identification of a disease-causing variant would also guide testing and diagnosis of at-risk relatives. This test is specifically designed for heritable germline mutations and is not appropriate for the detection of somatic mutations in tumor tissue.

PTEN: Deletion/duplication analysis covers the promoter region.

 
Reference Value (ค่าอ้างอิง):
An interpretive report will be provided.
 
Clinical Reference (เอกสารอ้างอิง):
www.invitae.com (Retrieved: 18 Mar 2021)