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Test Code:
090-10-0960

Order Name:
Hemosiderin (Random Urine)

 
Useful For:
Detecting hemosiderinuria, secondary to excess hemolysis, as in incompatible blood transfusions, severe acute hemolytic anemia, or hemochromatosis
 
Methodology:
Rous Method
 
 
 
Test Code:
090-10-0960

Order Name:
Hemosiderin (Random Urine)

 
Collection Specimen Or Container:
Urine/ Clean container 20 mL
 
Specimen Testing Type:
Urine, minimum volume 2 mL
 
Sub Mission Container:
Clean container
 
Specimen Stabillity:
Specimen Type Temperature Time
Random urine Room temperature, 18oC to 25oC 2 hours
 
 
 
Test Code:
090-10-0960

Order Name:
Hemosiderin (Random Urine)

 
Method detail:
Rous Method
 
Schedule:
Tested Daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1 hour
 
Performing Location:
Hematology, Laboratory Department Tel. 17254
 
Specimen Retention Time:
3 days
 
 
 
Test Code:
090-10-0960

Order Name:
Hemosiderin (Random Urine)

 
 
Clinical Information:
When the plasma hemoglobin level is >50 to 200 mg/dL after hemolysis, the capacity of haptoglobin to bind hemoglobin is exceeded, and hemoglobin readily passes through the glomeruli of the kidney. Part of the hemoglobin is absorbed by the proximal tubular cells where the hemoglobin iron is converted to hemosiderin. When these tubular cells are later shed into the urine, hemosiderinuria results. If all of the hemoglobin cannot be absorbed into the tubular cells, hemoglobinuria results.

Hemosiderin is found as yellow-brown granules that are free or in epithelial cells and occasionally in casts in an acidic or neutral urine.
 
Reference Value:
Negative
 
Interpretation:
A positive hemosiderin indicates excess red cell destruction.

Hemosiderinuria may still be detected after hemoglobin has cleared from the urine and hemoglobin dipstick is negative.
 
Clinical Reference:
http://www.mayomedicallaboratories.com (Retrieved: 22 Jan 2019)