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Test Code:
HDLC

Order Name:
HDL Cholesterol (HDL-C)

 
Useful For:
Cardiovascular risk assessment
 
Methodology:
Accelerator Selective Detergent
 
AliasesName:
​HDL-C
HDL Cholesterol
High Density Lipoprotein, Cholesterol
 
 
 
Test Code:
HDLC

Order Name:
HDL Cholesterol (HDL-C)

 
Patient Preparation:
  1. Patient should be fasting at least 12 hours.
  2. Patients should not drink any alcoholic beverages at least 24 hours.
  3. Patient can drink water as usual.
  4. Patient who takes the antihypertensive drugs, can take it as usual.
 
Collection Specimen Or Container:
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 0.5 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject 
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20o 3 months
 
 
 
Test Code:
HDLC

Order Name:
HDL Cholesterol (HDL-C)

 
Method detail:
Accelerator Selective Detergent
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
HDLC

Order Name:
HDL Cholesterol (HDL-C)

 
 
Clinical Information:
High-density lipoprotein (HDL) is the smallest of the lipoprotein particles and comprises a complex family of lipoprotein particles that exist in a constant state of dynamic flux as the particles interact with other HDL particles and with low-density lipoprotein (LDL) particles and very-low-density lipoprotein (VLDL) particles. HDL has the largest proportion of protein relative to lipid compared to other lipoproteins (>50% protein). Total cholesterol levels have long been known to be related to coronary heart disease (CHD). HDL cholesterol is also an important tool used to assess an individual's risk of developing CHD since a strong negative relationship between HDL cholesterol concentration and the incidence of CHD has been reported. In some individuals, exercise increases the HDL cholesterol level; those with more physical activity have higher HDL cholesterol values.
 
Reference Value:
Male: > 40 mg/dL
Female: > 50 mg/dL
 
Interpretation:
Low high-density lipoprotein (HDL) cholesterol correlates with increased risk for coronary heart disease (CHD). Values greater than or equal to 80 to 100 mg/dL may indicate metabolic response to certain medications such as hormone replacement therapy, chronic liver disease, or some form of chronic intoxication, such as with alcohol, heavy metals, or industrial chemicals including pesticides. HDL values of 5 mg/dL or less occur in Tangier disease, in association with cholestatic liver disease, and in association with diminished hepatocyte function.
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, Architect® Ultra HDL, Abbott Laboratories, Abbott Park IL 60064 USA, December 2014.
  2. http://www.ndei.org/ADA-diabetes-management-guidelines-cardiovasculardisease-CVD-management-lipids-BP.aspx.html (Retrieved: June 2018)
  3. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)