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Test Code:
HBSAG

Order Name:
HBsAg

 
Useful For:
Detection of hepatitis B surface antigen (HBsAg) in human serum.
 
Methodology:
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
AliasesName:
Hepatitis B Surface Antigen
Hepatitis Bs Ag
Hepatitis B Surface Ag
HBV surface antigen
 
 
 
Test Code:
HBSAG

Order Name:
HBsAg

 
Collection Specimen Or Container:
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 1 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum (keep in original tube) Refrigerated, 2oC to 8oC 8 hours
Serum Refrigerated, 2oC to 8oC 6 days
Frozen, -20oC 1 month
 
 
 
Test Code:
HBSAG

Order Name:
HBsAg

 
Method detail:
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 2 hours (120 mins)
 
Performing Location:
Immunology, Laboratory Department Tel. 13227
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
HBSAG

Order Name:
HBsAg

 
 
Clinical Information:
The causative agent of serum hepatitis is hepatitis B virus (HBV) which is an enveloped DNA virus. During infection, HBV produces an excess of hepatitis B surface antigen (HBsAg), also known as Australia antigen, which can be detected in the blood of infected individuals. It is responsible for binding the virus to the liver cell and is the target structure of neutralizing antibodies.  HBsAg is the first serological marker after infection with HBV appearing one to ten weeks after exposure and two to eight weeks before the onset of clinical symptoms.  HBsAg persists during this acute phase and clears late in the convalescence period. Failure to clear HBsAg within six months indicates a chronic HBsAg carrier state.  HBsAg assays are used to identify persons infected with HBV and to prevent transmission of the virus by blood and blood products as well as to monitor the stats of infected individuals in combination with other hepatitis B serological markers. 

In most countries, testing for HBsAg is part of the antenatal screening program to identify HBV infected mothers and to prevent perinatal HBV infection by subsequent immunization. 
 
Reference Value:
Non reactive 
 
Clinical Reference:
Manufacturer’s reagent package insert, Architect HBsAg Qualitative II, September 2013, Abbott Ireland Diagnostic Division, Finiskin Business Park, Sligo, Ireland.