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Test Code:
HBEAB

Order Name:
HBeAb

 
Useful For:
  1. Detection of antibody to hepatitis B e antigen (anti-HBe) in human serum.
  2. Indicated as an aid in the diagnosis and monitoring of hepatitis B viral infection.
 
Methodology:
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
AliasesName:
Anti-Hbe
Hepatitis Be Ab
Hepatitis Be Antibody
 
 
 
Test Code:
HBEAB

Order Name:
HBeAb

 
Collection Specimen Or Container:
Blood/ Plain Blood (Red Top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 1 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum (keep in original tube) Refrigerated, 2oC to 8oC 8 hours
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20oC 14 days
 
 
 
Test Code:
HBEAB

Order Name:
HBeAb

 
Method detail:
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 2 hours (120 mins)
 
Performing Location:
Immunology, Laboratory Department Tel. 13227
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
HBEAB

Order Name:
HBeAb

 
 
Clinical Information:
Hepatitis B e antigen (HBeAg) and its antibody (anti-HBe) are found in association with hepatitis B viral infection. HBeAg is first detectable in the early phase of hepatitis B viral infection, after the appearance of
hepatitis B surface antigen (HBsAg). The titers of both antigens rise rapidly during the period of viral replication in acute infection. Seroconversion from HBeAg to anti-HBe during acute hepatitis B infection is usually indicative of resolution of infection and a reduced level of infectivity. A negative HBeAg result may indicate (1) early acute infection before the peak of viral replication or (2) early convalescence when HBeAg has declined below detectable levels. The presence of anti-HBe serves to distinguish between these two phases. A subset of chronic hepatitis B patients have no detectable HBeAg in serum, but are positive for anti-HBe; these patients may also be positive for serum hepatitis B virus DNA.

Additionally HBe antigen/antibody seroconversion is used as an indicator of virological response when treating patients with chronic hepatitis B.
 
Reference Value:
Non reactive
 
Clinical Reference:
Manufacturer’s Reagent package insert, Architect Anti-HBe, February 2016, Abbott GmbH &Co.KG, MAX-Planck-Ring 2, 65205 Wiesbaden, Germany