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Clear
 
Test Code:
090-40-0150-01

Order Name:
Cryptococcus C/S (Source Specify)

 
Useful For:
Diagnosis of Cryptococcal infections
 
Methodology:
  1. Conventional Culture Technique
  2. Identification by MALDI-TOF
 
AliasesName:
Cryptococcus gattii
Cryptococcus neoformans
 
 
 
Test Code:
090-40-0150-01

Order Name:
Cryptococcus C/S (Source Specify)

 
Patient Preparation:
Medications: Do not use antibiotics before collection of specimen
 
Collection Specimen Or Container:
CSF/ Sterile container
  1. 1. Disinfect site with iodine or chlorhexidine preparation.
  2. 2. Insert a needle with stylet at L3-L4, L4-L5, or L5-S1 interspace.
  3. 3. Upon reaching the subarachnoid space, remove the stylet and collect 1–2 ml of fluid into each of three leakproof containers
 
Specimen Testing Type:
CSF, minimum volume 1 mL.
 
Sub Mission Container:
If only one container of CSF is collected, it should be submitted to microbiology first; otherwise, submit container 2nd to microbiology.
 
Rejection Criteria:
Specimen in formalin or refrigerated will be rejected.
 
Specimen Stabillity:
Specimen Type Temperature Time
CSF Room temperature, 18oC to 25oC 24 hours
 
 
 
Test Code:
090-40-0150-01

Order Name:
Cryptococcus C/S (Source Specify)

 
Method detail:
  1. Conventional Culture Technique
  2. Identification by MALDI-TOF
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Received specimen to report within 3 days.
 
Performing Location:
Microbiology, Laboratory Department Tel. 14171
 
Specimen Retention Time:
1 month
 
 
 
Test Code:
090-40-0150-01

Order Name:
Cryptococcus C/S (Source Specify)

 
 
Clinical Information:
Cryptococcosis is an invasive fungal infection caused by Cryptococcus neoformans or C gattii. C neoformans has been isolated from several sites in nature, particularly weathered pigeon droppings. C gatti was previously only associated with tropical and subtropical regions; however, more recently this organism has also been found to be endemic in British Columbia and among the Pacific Northwest United States, and is associated with several different trees species.
 
Reference Value:
No Cryptococcal growth
 
Interpretation:
Cryptococcal meningitis (CM) is a central nervous system infectious disease caused by Cryptococcus. It is the most common fungal infection in the central nervous system, accounting for about 48% of fungal infection. The disease occurs mainly in acquired immunodeficiency syndrome (AIDS) patients and concentrates in the immunocompromised people without AIDS
 
Clinical Reference:
  1. Manufacturer’s package insert, CALAS, Meridian Diagnostic, USA 2. https://www.mayocliniclabs.com (Retrieved: 29 Jan 2019)
  2. Amy L. Leber, editor. Clinical Microbiology Procedure Handbook 4th Edition. Washington DC: American Society for Microbiology; 2016
  3. James H. Jorgensen, Michael A. PFALLER. Manual of Clinical Microbiology 11th ed. Washington, DC: ASM Press; 2015