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Clear
 
Test Code:
090-80-1060-01

Order Name:
Copper (Blood)

 
Useful For:
Diagnosis of:
  • Wilson disease
  • Primary biliary cirrhosis
  • Primary sclerosing cholangitis
 
Methodology:
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
 
AliasesName:
Cu (Copper), Blood
 
 
 
Test Code:
090-80-1060-01

Order Name:
Copper (Blood)

 
Collection Specimen Or Container:
Blood/ K2EDTA (Royal blue-top) 6 mL, 1 tube
 
Specimen Testing Type:
K2EDTA Whole blood, minimun 5 mL 
 
Sub Mission Container:
Plastic vial (PP Grade)
 
Rejection Criteria:
Hemolyse: 1+ reject
 
Specimen Stabillity:
Specimen Type Temperature Time
K2EDTA blood (keep in original tube) Refrigerated, 2oC to 8oC 14 days
 
 
 
Test Code:
090-80-1060-01

Order Name:
Copper (Blood)

 
Method detail:
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)
 
Schedule:
Tested on Tuesday and Friday at 7.00 a.m.
 
Turnaround Time:
Result reporting within Wednesday or Saturday, before 3.00 p.m.
 
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
1 month
 
 
 
Test Code:
090-80-1060-01

Order Name:
Copper (Blood)

 
 
Clinical Information:
The most oxidation numbers of copper in living organisms are Cu(II) and Cu(I). The essential trace element copper is a cofactor of many enzymes involved in redox reactions, such as cytochrome c oxidase, ascorbate oxidase, or superoxide dismutase. In addition to its enzymatic roles, copper is used in biological systems for electron transport (Valko et al., 2005). The blue copper proteins that participate in electron transport include azurin and plastocyanin.
 
Reference Value:
Copper (Blood)
Sex Reference value Unit
Male 800 - 1,100 µg/L
Female 1,100 - 1,400 µg/L
 
Interpretation:
Level of copper can effect to Cancer, Neurological disorders such as Alzheimer‘s disease (AD), and Parkinson‘s disease (PD), Chronic disease: diabetes, cardiovascular disease and atherosclerosis.
 
Clinical Reference:
  1. แสงโฉม เกิดคล้าย, บรรณาธิการ. แนวทางการวินิจฉัยเพื่อการรายงานโรคจากการประกอบอาชีพและ สิ่งแวดล้อม. พิมพ์ครั้งที่1. สำนักระบาดวิทยา กรมควบคุมโรค กระทรวงสาธารณสุข. สิงหาคม 2547:หน้า 22-33
  2. NCCLS document C38-A, Control of Pre analytical Variation in trace Element Determinations; Approved Guideline, 1997
  3. Biomarker Testing of Industrial Chemicals; Version 2018
  4. www.Thaitox.com
  5. The handbook of Environmental Chemistry Volume 3 Part A, Handbook on the toxicology of metals. Volume I., Ärztlicher Befundbericht, IMD Institut für Medizinische Diagnostik Berlin-Potsdam GbR, Nicolaistraße 22 - 12247 Berlin (Steglitz).
  6. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)
  7. K. Jomova, M. Valko, Advances in metal-induced oxidative stress and human disease, Toxicology 283 (2011) 65–87