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Test Code:
090-20-0260-01

Order Name:
Chloride (Random Urine)

 
Useful For:
An indicator of fluid balance and acid-base homeostasis
 
Methodology:
Ion-selective electrode diluted (Indirect)
 
AliasesName:
Cl (Chloride), Random urine
 
 
 
Test Code:
090-20-0260-01

Order Name:
Chloride (Random Urine)

 
Collection Specimen Or Container:
Urine, Clean container
 
Specimen Testing Type:
Urine, minimum volume 10 mL
 
Sub Mission Container:
Clean container
 
Rejection Criteria:
Hemolysis: 4+ reject
 
Specimen Stabillity:
Specimen Type Temperature Time
Random urine Refrigerated, 2oC to 8oC 7 days
Frozen, -20oC 7 days
 
 
 
Test Code:
090-20-0260-01

Order Name:
Chloride (Random Urine)

 
Method detail:
Ion-selective electrode diluted (Indirect)
 
Schedule:
Tested daily (24 Hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
7 days
 
 
 
Test Code:
090-20-0260-01

Order Name:
Chloride (Random Urine)

 
 
Clinical Information:
Chloride is the major extracellular anion. Its precise function in the body is not well understood; however, it is involved in maintaining osmotic pressure, proper body hydration, and electric neutrality. In the absence of acid-base disturbances, chloride concentrations in plasma will generally follow those of sodium (Na+). Since urine is the primary mode of elimination of ingested chloride, urinary chloride excretion during steady state conditions will reflect ingested chloride, which predominantly is in the form of sodium chloride (NaCl). However, under certain clinical conditions, the renal excretion of chloride may not reflect intake. For instance, during states of extracellular volume depletion, urine chloride (and sodium) excretion is reduced.
 
Reference Value:
No reference ranges established.
 
Interpretation:
Urine sodium and chloride excretion are similar and, under steady state conditions, both the urinary sodium and chloride excretion reflect the intake of sodium chloride (NaCl). During states of extracellular volume depletion, low values indicate appropriate renal reabsorption of these ions, whereas elevated values indicate inappropriate excretion (renal wasting). Urinary sodium and chloride excretion may be dissociated during metabolic alkalosis with volume depletion where urine sodium excretion may be high (due to renal excretion of NaHCO3) while urine chloride excretion remains appropriately low.
 
Clinical Reference:
  1. Manufacturer’s reagent package insert, Architect® ICT (Na+, K+, Cl-) Sample Diluent, Abbott Laboratories, Diagnostic Division, Abbott Park IL 60064, May 2016.
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)