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Clear
 
Test Code (รหัสการทดสอบ):
CK

Order Name (ชื่อการทดสอบ):
CPK

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 1.5 hours (90 mins)
 
Useful For (ประโยชน์การทดสอบ):
Diagnosing and monitoring myopathies or other trauma, toxin, or drug-induced muscle injury
 
Methodology (วิธีการทดสอบ):
NAC (N-acetyl-L-cysteine)
 
AliasesName (ชื่อเรียกอื่นๆ) :
CK
Creatine Kinase
 
 
 
Test Code (รหัสการทดสอบ):
CK

Order Name (ชื่อการทดสอบ):
CPK

 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 0.5 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic vial
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Hemolysis: Mild or above reject
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 7 days
 
 
 
Test Code (รหัสการทดสอบ):
CK

Order Name (ชื่อการทดสอบ):
CPK

 
Method detail (วิธีการทดสอบ):
NAC (N-acetyl-L-cysteine)
 
Schedule (ตารางการทดสอบ):
Tested daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
CK

Order Name (ชื่อการทดสอบ):
CPK

 
 
Clinical Information (ข้อมูลทางคลินิก):
Measurements of creatine kinase are used in the diagnosis and treatment of diseases associated with skeletal muscle, heart, central nervous system, and thyroid.
 
Reference Value (ค่าอ้างอิง):
Male: 30 – 200 U/L
Female: 29 – 168 U/L
 
Interpretation (การแปลผล):
Serum creatine kinase (CK) activity may increase in patients with acute cerebrovascular disease or neurosurgical intervention and with cerebral ischemia as well as in nearly all patients when injury, inflammation, or necrosis of skeletal or heart muscle occurs, including: - All types of muscular dystrophy particularly in progressive muscular dystrophy (particularly Duchenne sex-linked muscular dystrophy). - Viral myositis, polymyositis, and similar muscle diseases - Malignant hyperthermia, an inherited life-threatening condition characterized by high fever and brought on by administration of inhalation anesthesia - Muscle trauma, which causes CK elevations within 12 hours of onset, peaking within 1 to 3 days, and declining 3 to 5 days after cessation of muscle injury - Serum CK activities exceeding 200 times the upper reference limit may be found in acute rhabdomyolysis, putting the patient at great risk for developing acute renal failure. - When given at pharmacologic doses, some drugs including statins, fibrates, antiretrovirals, and angiotensin II receptor antagonists - Endocrine myopathy, for which hpothyroidism is a common cause, about 60% of hypothyroid subjects show an average elevation of CK activity 5-fold greater than the upper reference limit - Normal childbirth causes a 6-fold elevation in maternal serum For detection of myocardial infarction, changes in serum CK and its heart tissue (MB) isoenzyme have been largely replaced by the more cardiac-specific nonenzymatic markers, cardiac troponin I or T.
 
Clinical Reference (เอกสารอ้างอิง):
  1. Manufacturer’s reagent package insert, Architect® Creatine Kinase, Abbott Laboratories, Diagnostic Division, Abbott Park IL 60064 USA, November 2015
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)