bih.button.backtotop.text
BROWSE BY TEST NAME
%
1
2
3
5
8
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Clear
 
Test Code (รหัสการทดสอบ):
ADNAA

Order Name (ชื่อการทดสอบ):
Anti dsDNA ( Anti double stranded DNA ) by IFA

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Specimen received to reported within 2 days.
 
Useful For (ประโยชน์การทดสอบ):
Diagnosis of systemic lupus erythematosus (SLE) in the suspected patient.
 
Methodology (วิธีการทดสอบ):
Indirect immunofluorescence assay
 
AliasesName (ชื่อเรียกอื่นๆ) :
Antibody to ds-DNA
Antibody to Native DNA (n-DNA)
Anti-DNA
Anti-ds (Anti-Double Stranded) DNA
ANTI-dsDNA ANTIBODY, IgG
DNA Double Stranded (ds-DNA) Antibody
 
 
 
Test Code (รหัสการทดสอบ):
ADNAA

Order Name (ชื่อการทดสอบ):
Anti dsDNA ( Anti double stranded DNA ) by IFA

 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 0.5 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic tube
 
Rejection Criteria (เกณฑ์ปฏิเสธสิ่งส่งตรวจ):
Hemolysis: N/A
Lipemia: N/A
Icterus: N/A
Other: Heat-treated specimen will be reject.
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 14 days
 
 
 
Test Code (รหัสการทดสอบ):
ADNAA

Order Name (ชื่อการทดสอบ):
Anti dsDNA ( Anti double stranded DNA ) by IFA

 
Method detail (วิธีการทดสอบ):
Indirect immunofluorescence assay
 
Schedule (ตารางการทดสอบ):
Test daily, at 03:00 p.m.
 
Turnaround Time (ระยะเวลารอผล):
Specimen received to reported within 2 days.
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Molecular biology & Genetics, Laboratory Department Tel.14168
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
7 days
 
 
 
Test Code (รหัสการทดสอบ):
ADNAA

Order Name (ชื่อการทดสอบ):
Anti dsDNA ( Anti double stranded DNA ) by IFA

 
 
Clinical Information (ข้อมูลทางคลินิก):
Systemic lupus erythematosus is a systemic autoimmune disease belonging to the collagenosis group. Diagnosis of SLE is base on the 11 ACR criteria (ACR = American College of Rheumatology) . If 4 of 11 criteria are present, the probability of SLE presence is between 80 and 90%. Antibodies against dsDNA are among the most important criteria of diagnosis of SLE due to their high specificity: 70% to 98% depending on the method of detection. Since the concentration of these antibodies correlates with the disease activity, particularly with the activity of lupus nephritis, titer deteminations are suitable for monitoring therapy.
 
Reference Value (ค่าอ้างอิง):
Negative
 
Interpretation (การแปลผล):
Anti-dsDNA antibodies are found almost exclusively in systemic SLE, also known as lupus erythematosus disseminatus. The prevalence of antibodies against dsDNA amounts to 20% to 90% depending on the detection method and disease activity. Antibodies against dsDNA are also occasionally detected in patient with other autoimmune diseases and infection and in rare cases, in clinically healthy people. 85% of people in the latter group develop SLE within 5 years of initial detection of anti-dsDNA. However, SLE cannot be entirely excluded if anti-dsDNA antibodies are not detected.
 
Clinical Reference (เอกสารอ้างอิง):
Manufacturers’s package insert, Crithidia luciliae (anti-dsDNA) instructions for the indirect immunofluorescence test, January 2017, EUROIMMUN, D-23560 Lübeck Germany.