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Test Code:
AMS

Order Name:
Amylase

 
Useful For:
Diagnosing acute pancreatitis
 
Methodology:
CNPG3 Substrate
 
 
 
Test Code:
AMS

Order Name:
Amylase

 
Collection Specimen Or Container:
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type:
Serum, minimum volume 0.5 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 3+ or above reject
 
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20oC 12 months
 
 
 
Test Code:
AMS

Order Name:
Amylase

 
Method detail:
CNPG3 Substrate
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
AMS

Order Name:
Amylase

 
 
Clinical Information:
Normal individuals have low but measurable serum and urine α‑amylase activity which is produced in the pancreas and parotid glands. Measurement of α-amylase activity is of value in diagnosing pancreatitis and other pancreatic disorders which result in elevation of serum and urine α-amylase activity.
 
Reference Value:
25 – 125 U/L
 
Interpretation:
Pancreatic amylase is elevated in acute pancreatitis within 12 hours of onset and persists 3 to 4 days. The elevation is usually 4-fold to 6-fold the upper reference limit. Macroamylase may cause less dramatic and more persistent elevations of p-amylase over weeks or months. This is usually accompanied by a reduced amylase clearance.
 
Values over the normal reference interval in patients with histories consistent with acute pancreatitis are confirmatory. Peak values are often 200 U/L or higher. Macroamylasemia may cause small, but persistent elevations of amylase. 

An elevation of total serum alpha-amylase does not specifically indicate a pancreatic disorder since the enzyme is produced by the salivary glands, mucosa of the small intestine, ovaries, placenta, liver, and the lining of the fallopian tubes. Two isoenzymes, pancreatic and salivary, are found in serum. Pancreatic amylase has been shown to be more useful than total amylase when evaluating patients with acute pancreatitis.
 
Clinical Reference:
1. Manufacturer’s reagent package insert, Architect® Amylase,
    ABBOTT Laboratories, Diagnostic Division, Abbott Park IL 60064 USA, August 2015.
2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019)