Will it hurt?

No. During a colonoscopy, patients will receive a sedative through their vein to help keep them relaxed. After the colonoscopy, patients will be taken care of in a recovery room for about two hours. Cramping or bloating may occur during the first hour after the procedure because of some pumped-in air left in the abdomen. Patients will feel better after flatulating. This symptom will disappear within 24 hours.