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Test Code:
VMAU24HR

Order Name:
Vanillylmandelic Acid (VMA) (U-24 hrs.)

 
Useful For:
Diagnosis of neuroendocrine tumors including neuroblastomas, pheochromocytoma and paraglanglioma.
 
Methodology:
High Performance Liquid Chromatography (HPLC)
 
AliasesName:
VMA, U-24 hrs.
Vanillylmandelic Acid, U-24 hrs.
Adernaline degradation product, U-24 hrs.
 
 
 
Test Code:
VMAU24HR

Order Name:
Vanillylmandelic Acid (VMA) (U-24 hrs.)

 
Patient Preparation:
Administration of L-dopa may falsely-increase vanillylmandelic acid results; it should be discontinued 24 hours prior to and during collection of specimen
 
Collection Specimen Or Container:
24-hours urine/ Clean container with preservative (25% HCl - 10 mL)
* 24-hours volume is required.
 
Specimen Testing Type:
Preserved 24- hour Urine in 25% HCl minimum volume 10 mL
 
Sub Mission Container:
15 mL Screw cap tube
 
Rejection Criteria:
 No preservative urine will be rejected.
 
Specimen Stabillity:
 
Specimen Type Temperature Time
24-hours urine Refrigerated, 2oC to 8oC 14 days
Frozen, -18 oC 3 months
 
 
 
Test Code:
VMAU24HR

Order Name:
Vanillylmandelic Acid (VMA) (U-24 hrs.)

 
Method detail:
High Performance Liquid Chromatography (HPLC)
 
Schedule:
Every Thursday
 
Turnaround Time:
Received specimen to reported within 7 Days.
 
Performing Location:
Special Lab, Laboratory Department 14141
 
Specimen Retention Time:
7 days
 
 
 
Test Code:
VMAU24HR

Order Name:
Vanillylmandelic Acid (VMA) (U-24 hrs.)

 
 
Clinical Information:
Vanillylmandelic acic (VMA) are degradation product of adernaline.
 
Reference Value:
Age Reference Value Unit
Adult 1,600 - 7,300 microgram/ 24h
Children 0 - 2 weeks 0 - 850 microgram/24 h
2 - 8 weeks 0 - 1,300 microgram/24 h
2 - 6 months 0 - 1,500 microgram/24 h
7 - 12 months 0 - 1,700 microgram/24 h
1 - 5 years 0 - 2,200 microgram/24 h
6 - 10 years 0 - 3,600 microgram/24 h
11 - 15 years 0 - 4,800 microgram/24 h
 
Interpretation:
High level of VMA was found in neuroendocrine tumors including neuroblastomas, pheochromocytoma and paraglanglioma.
 
Clinical Reference:
Instrucition manual for HPLC determination of VMA, HVA, 5-HIAA in Urine