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Test Code:
090-30-1421-01

Order Name:
Valproic Acid (Depakine), (Blood)*

 
Useful For:
Used for the quantitative in vitro measurement of valproic acid in human serum.
 
Methodology:
Particle-enhanced turbidimetric inhibition immunoassay (PETINIA)
 
AliasesName:
Valproic acid
Depakene
 
 
 
Test Code:
090-30-1421-01

Order Name:
Valproic Acid (Depakine), (Blood)*

 
Patient Preparation:
Follow by Physician or Pharmacist recommedation.
 
Collection Specimen Or Container:
Plain Blood 6 mL (Red Top) 1 tube
 
Specimen Testing Type:
Serum, minimum volume 0.5 mL
 
Sub Mission Container:
Plastic vial
 
Rejection Criteria:
Hemolysis: 4+ reject
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum (keep in original tube) Refrigerated, 2oC to 8oC 8 hours
Serum Refrigerated, 2oC to 8oC 48 hours
Frozen, -20oC 7 days
 
 
 
Test Code:
090-30-1421-01

Order Name:
Valproic Acid (Depakine), (Blood)*

 
Method detail:
Chemiluminescent Microparticle Immuno Assay (CMIA)
 
Schedule:
Tested daily (24 hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
 
Performing Location:
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time:
5 days
 
 
 
Test Code:
090-30-1421-01

Order Name:
Valproic Acid (Depakine), (Blood)*

 
 
Clinical Information:
Valproic acid (VPA; 2-propylpentanoic acid; Depakene) is a broad-spectrum anticonvulsant drug used solely or in combination with other anticonvulsant drugs for the treatment of absence seizures. It also has demonstrated effectiveness in the management of generalized tonic-clonic and myoclonic seizures, as well as atypical absence, simple and complex partial, and mixed grand mal and petitmal seizures. The capability of treating many types of seizures with a single anticonvulsant has resulted in the widespread use of valproic acid, particularly in children in whom tonic-clonic and myoclonic seizures are most prevalent. Valproic acid has proven effective in the treatment of many patients otherwise refractory to other anticonvulsant treatments. Most patients receiving valproic acid do not develop a tolerance to its anticonvulsant effects.
 
Reference Value:
Trough level: 50 - 100 µg/mL 
 
Clinical Reference:
Manufacturer’s reagent package insert, Architect® /Aeroset® Valproic acid, ABBOTT Microgenics Corporation 46360 Fremont Blvd. Fremont CA, USA, August 2016.