These tests can predict which patients are at higher risk, and therefore might benefit from adjuvant therapy, as well as other endpoints that can positively impact a patient’s journey.
The Tempus Homologous Recombination Deficiency (HRD) test is a DNA-based test, available as part of the xT platform, for clinicians aiming to better understand if their patient has Homologous Recombination Deficiency. Tempus HRD is a comprehensive view into a patient’s ability to repair double-stranded DNA breaks. HRD status can be used to identify patients who may be sensitive to PARP inhibitors and/or platinum-based chemotherapy.
The Tempus HRD test takes into account results from our xT Sequencing Panel, giving a full view into 18 commonly mutated genes in the HR-pathway, along with a genome wide loss-of-heterozygosity (LOH) score, giving a clinician one of the most complete views of HRD status on the market. The HRD test can be ordered with 6 major cancer subtypes: Ovarian, Breast, Pancreatic, Prostate, Non-small-cell lung cancer, and Glioblastoma, and does not require additional tissue from the patient.