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Test Code:
092-10-0008

Order Name:
Oncomine™ Pan‑Cancer Cell‑Free Panel

 
Useful For:
The detection of relevant SNVs, CNVs, gene fusions, and indels from 52 unique genes to help inform drug discovery research and clinical trial research programs.

Gene List:
-  Full-length genes:
      APC, FBXW7, PTEN, TP53

- Hotspot genes:
      AKT1, ALK, AR, ARAF, BRAF, CHEK2, CTNNB1, DDR2,EGFR, ERBB2, ERBB3, ESR1, FGFR1,
      FGFR2, FGFR3, FGFR4, FLT3, GNA11, GNAQ, GNAS, HRAS, IDH1, IDH2, KIT, KRAS, MAP2K1,
      MAP2K2, MET, MTOR, NRAS, NTRK1, NTRK3, PDGFRA, PIK3CA, RAF1, RET, ROS1, SF3B1,
      SMAD4, SMO

- Copy number variations genes (CNVs):
      CCND1, CCND2, CCND3, CDK4, CDK6, EGFR, ERBB2, FGFR1, FGFR2, FGFR3, MET, MYC

- Gene fusions:
      ALK, BRAF, ERG, ETV1, FGFR1, FGFR2, FGFR3, MET, NTRK1, NTRK3, RET, ROS1
 
Methodology:
Next generation sequencing (NGS), Target sequencing
 
AliasesName:
Cell-free DNA
cfDNA
ctDNA
Liquid biopsy
 
 
 
Test Code:
092-10-0008

Order Name:
Oncomine™ Pan‑Cancer Cell‑Free Panel

 
Collection Specimen Or Container:
Blood/ Streck 10 mL, 2 tubes
 
Specimen Testing Type:
Whole blood 10 mL Streck tube, 2 tubes
 
Sub Mission Container:
Streck tube
 
Specimen Stabillity:
Specimen Type Temperature Time
Whole blood Ambient temperature 7 days
 
 
 
Test Code:
092-10-0008

Order Name:
Oncomine™ Pan‑Cancer Cell‑Free Panel

 
Method detail:
Next generation sequencing (NGS), Target sequencing
 
Turnaround Time:
Reported within 30 days
 
Performing Location:
Research and Development Tel. 14252
 
Specimen Retention Time:
1 day
 
 
 
Test Code:
092-10-0008

Order Name:
Oncomine™ Pan‑Cancer Cell‑Free Panel

 
 
Clinical Information:
The OncomineTM Pan-Cancer Cell-Free Panel detect multiple mutations in tumor-derived DNA and RNA isolated from the plasma fraction of whole blood. These 52 genes have been identified as frequently mutated in multiple cancer types, including: bladder, brain and CNS, breast, cervical, colorectal, endometrial, esophageal, gastric, head and neck, kidney, liver, lung, melanoma, ovarian, pancreatic, prostate, sarcoma, and thyroid.
 
Clinical Reference:
https://www.thermofisher.com/order/catalog/product/A37664 (Retrieved 1 Feb 2019)