Determine a healthy adult's predisposition to cancer, cardiovascular conditions, and more.
If you checked "No" to all questions, your patient is likely a good candidate for Proactive genetic testing
. If you checked "Yes" for any of the boxes above, you may want to consider further evaluation to determine whether Diagnostic testing is more appropriate for your patient.
Do any of the following apply to your patient or their close blood relative* ?
- Early-onset breast cancer (at age 45 or younger), triple-negative breast cancer (ER-, PR-, HER2-; at age 60 or younger), breast cancer in a male, or breast cancer in an individual with Ashkenazi Jewish ancestry
- Ovarian cancer
- Colorectal cancer or endometrial cancer (younger than age 50) Diffuse gastric cancer
- Metastatic prostate cancer
- Pancreatic cancer
- 10 or more colon polyps
- Diagnosis of a potentially hereditary cardiovascular condition such as cardiomyopathy2, arrhythmia3, aortopathy4, familial hypercholesterolemia, pulmonary arterial hypertension, or hereditary hemorrhagic telangiectasia
- Early-onset cardiovascular disease:
- ICD/Pacemaker (younger than age 50)
- Heart failure or heart transplant (younger than age 60)
- Early "heart attack", coronary artery disease, or stroke (males younger than age 55; females younger than age 65)
- Aortic aneurysm/dissection (younger than age 50)
- Untreated LDL ≥190
- Unexplained cardiac arrest(s) or sudden death, or sudden infant death syndrome (SIDS)
- Unexplained syncope or syncope with exercise or emotional distress
*Close blood relatives include sibling, half-sibling, parent, child, aunt/uncle, niece/nephew, grandparent, or grandchild