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Test Code:
098-10-0003-01

Order Name:
Homovanillic Acid (HVA) (U-24 hrs.)

 
Useful For:
Diagnosis of neuroendocrine tumors including neuroblastomas, pheochromocytoma and paraglanglioma.
 
Methodology:
High Performance Liquid Chromatography (HPLC)
 
AliasesName:
HVA, U-24 hrs.
 
 
 
Test Code:
098-10-0003-01

Order Name:
Homovanillic Acid (HVA) (U-24 hrs.)

 
Patient Preparation:
No prescription of acetanilide, caffeine, coumarin, ephedrine-HCl, mephenesin, metamphetamine, methocarbamol, nicotine, paracetamol, phenacetin, phenobarbital, phentolamine aspirin, chlorpromazine, isoniazid, levodopa, methenamine, promethazine, streptozocin for 24Hrs prior to collect urine.
 
Collection Specimen Or Container:
24-hours urine/ Clean container with preservative (25% HCl - 10 mL)
* 24-hours volume is required.
 
Specimen Testing Type:
Preserved 24- hour Urine in 25% HCl minimum volume 10 mL
 
Sub Mission Container:
15 mL Screw cap tube
 
Rejection Criteria:
 No preservative Urine will be rejected.
 
Specimen Stabillity:
 
Specimen Type Temperature Time
24-hours urine Refrigerated, 2oC to 8oC 14 days
Frozen, -18oC 3 months
 
 
 
Test Code:
098-10-0003-01

Order Name:
Homovanillic Acid (HVA) (U-24 hrs.)

 
Method detail:
High Performance Liquid Chromatography (HPLC)
 
Schedule:
Every Thursday
 
Turnaround Time:
Received to Reported within 7 Days.
 
Performing Location:
Special Lab, Laboratory Department 14141
 
Specimen Retention Time:
7 days
 
 
 
Test Code:
098-10-0003-01

Order Name:
Homovanillic Acid (HVA) (U-24 hrs.)

 
 
Clinical Information:
Homovanillic acid (HVA) are degradation product of Noradernaline.
 
Reference Value:
Age Reference Value Unit
Adult 1,800 - 6,900 microgram/24 h
Children 0 - 2 weeks 0 - 1,500 microgram/24 h
2 - 8 weeks 0 - 2,000 microgram/24 h
2 - 6 months 0 - 2,900 microgram/24 h
7 - 12 months 0 - 3,400 microgram/24 h
1 - 5 years 0 - 4,800 microgram/24 h
6 - 10 years 0 - 6,900 microgram/24 h
11 - 15 years 0 - 8,800 microgram/24 h
 
Interpretation:
High level of HVA was found in neuroendocrine tumors including neuroblastomas, pheochromocytoma and paraglanglioma.
 
Clinical Reference:
Instruction manual for HPLC determination of VMA, HVA, 5-HIAA in Urine