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Clear
 
Test Code:
090-71-5021

Order Name:
HLA-B27 **

 
Useful For:
Assisting in the diagnostic process of ankylosing spondylitis (AS), juvenile rheumatoid arthritis, and Reiter syndrome
 
Methodology:
Polymerase chain reaction
 
AliasesName:
HLA-B 27
B27 Histocompatibility Antigen
Human Leukocyte Antigen
Leukocyte Antigens LY27
Spondylitis W-27 (HLA-B27)
 
 
 
Test Code:
090-71-5021

Order Name:
HLA-B27 **

 
Collection Specimen Or Container:
Blood/ K3 EDTA (Lavender Top) 3 mL, 1 tube
 
Specimen Testing Type:
Whole Blood EDTA, minimum volume 3 mL
 
Sub Mission Container:
Original tube
 
Rejection Criteria:
Hemolysis: Hemolysis interfere
Other: Over Stability / Frozen specimen will be reject.
 
Specimen Stabillity:
Specimen Type Temperature Time
Whole blood, EDTA Ambient (preferred) Same day
Refrigerated, 2oC to 8oC 7 days
 
 
 
Test Code:
090-71-5021

Order Name:
HLA-B27 **

 
Method detail:
Polymerase chain reaction
 
Schedule:
N/A **Sent Out to Ramathibodi
 
Turnaround Time:
Reported within 3-5 days (exception for official holidays)
 
Performing Location:
Ramathibodi
Referral Lab Services, Laboratory Department 14160-2
 
 
 
Test Code:
090-71-5021

Order Name:
HLA-B27 **

 
 
Clinical Information:
This major histocompatibility coded class I antigen is associated with ankylosing spondylitis, juvenile rheumatoid arthritis, and Reiter syndrome. The mechanism of the association is not understood but probably is that of linkage disequilibrium. There is an increased prevalence of HLA-B27 in certain rheumatic diseases, particularly ankylosing spondylitis.
 
Reference Value:
Negative
 
Interpretation:
Approximately 8% of the normal population carries the HLA-B27 antigen. HLA-B27 is present in approximately 89% of patients with ankylosing spondylitis, 79% of patients with Reiter syndrome, and 42% of patients with juvenile rheumatoid arthritis. However, lacking other data, it is not diagnostic for these disorders.
 
Clinical Reference:
www.mayomedicallaboratories.com (Retrieved: 23 Jan 2019)