Order Name (ชื่อการทดสอบ):
Genetic Health Screen (cancer and cardio) using whole exome sequencing (WES)
Clinical Information (ข้อมูลทางคลินิก):
Genetic Health Screen include cancer screen and cardio screen. For cancer screen, more than 90 genes related with variety type of inherited cancers includung Breast, Ovarian, Colorectal, Melanoma, Gastric cancer, Pancreatic, Prostate, Renal, Parathyroid, Pituitary adenoma, Neuroblastoma, leukemia, and other familial cancer syndromes were analzyed and reported. For cardio screen, more than 95 genes related with cardiovascular conditions including Aortopathies, Arrhythmias, Cardiomyopathies, Thrombophilia, Neuromuscular condition, Hypercholesterolemia, congenital heart disease, Pulmonary hypertension, and Other heart syndromes were analzyed and reported.
Clinical Reference (เอกสารอ้างอิง):
1. https://www.omim.org (Retrieved 1 July 2022)
2.https://www.cancer.gov/publications/dictionaries/cancer-terms/def/inherited-cancer-syndrome ((Retrieved 1 July 2022)
3. Cirino AL, Harris S, Lakdawala NK, et al. Role of Genetic Testing in Inherited Cardiovascular Disease: A Review. JAMA Cardiol. 2017;2(10):1153–1160. doi:10.1001/jamacardio.2017.2352