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Clear
 
Test Code:
090-31-2800-01

Order Name:
Gastrin **

 
Useful For:

Investigation of patients with achlorhydria or pernicious anemia

Investigation of patients suspected of having Zollinger-Ellison syndrome

Diagnosis of gastrinoma

 
Methodology:
Automated Chemiluminescent Immunometric Assay
 
AliasesName:
ACh Receptor (Muscle) Binding Ab
Acetylcholine Receptor (Muscle AChR) Binding Antibody, Serum
Acetylcholine Receptor (Muscle AChR) Antibodies
AChR (Acetylcholine Receptor)
Anti -Neuromuscular Junction Receptor Antibodies
Myasthenia Gravis Antibodies
 
 
 
Test Code:
090-31-2800-01

Order Name:
Gastrin **

 
Patient Preparation:
  • Fasting (8 hours) required
  • For 12 hours before specimen collection, do not take multivitamins or dietary supplements containing biotin (vitamin B7), which is commonly found in hair, skin, and nail supplements and multivitamins.
  • If medically feasible, proton pump inhibitor (omeprazole, lansoprazole, dexlansoprazole, esomeprazole, pantoprazole, and rabeprazole) therapy should be discontinued 1 week before measurement of serum gastrin levels.
  • Drugs that interfere with gastrointestinal motility (eg, opioids) should be discontinued for at least 2 weeks before serum gastrin testing.
 
Collection Specimen Or Container:
Blood/ Plain blood (Red top) 6 mL, 2 tubes
 
Specimen Testing Type:
Serum, minimum volume 1 mL x 2 tubes
Centrifuge at refrigerated temperature within 2 hours of collection and immediately aliquot serum into plastic vial.
 
Sub Mission Container:
Plastic tube
 
Rejection Criteria:
Hemolysis: Gross reject
Lipemia: OK
 
Specimen Stabillity:
Specimen Type Temperature Time
Serum Frozen (preferred) 30 days
Serum Refrigerated, 2oC to 8oC 24 hours
 
 
 
Test Code:
090-31-2800-01

Order Name:
Gastrin **

 
Method detail:
Automated Chemiluminescent Immunometric Assay
 
Schedule:
N/A **Sent out to MAYO, USA
 
Turnaround Time:
Received specimen to report within 14 days
 
Performing Location:
MAYO Laboratory
Referral Lab Services, Laboratory Department 14160-2
 
 
 
Test Code:
090-31-2800-01

Order Name:
Gastrin **

 
 
Clinical Information:
Serum gastrin levels may also be elevated in gastric distention due to gastric outlet obstruction and in a variety of conditions that lead to real or functional gastric hypo- or achlorhydria (gastrin is secreted in an attempted compensatory response to achlorhydria). These include atrophic gastritis with or without pernicious anemia, a disorder characterized by destruction of acid-secreting (parietal) cells of the stomach; gastric dumping syndrome; and surgically excluded gastric antrum. In atrophic gastritis, the chronic cell-proliferative stimulus of the secondary hypergastrinemia may contribute to the increased gastric cancer risk observed in this condition.
 
Reference Value:

<100 pg/mL

There is no evidence that fasting serum gastrin levels differ between adults and children. Although 8-hour fasts are difficult or impossible to enforce in small children, serum gastrin levels after shorter fasting periods (3-8 hours) may be 50% to 60% higher than the 8-hour fasting value.

 
Clinical Reference:
www.mayocliniclabs.com (Retrieved: 27 Jun 2020)