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Clear
 
Test Code (รหัสการทดสอบ):
CR

Order Name (ชื่อการทดสอบ):
Creatinine and eGFR

 
Specimen / Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 90 min
 
Useful For (ประโยชน์การทดสอบ):
Creatinine:
  • Diagnosing and monitoring treatment of acute and chronic renal diseases.
  • Adjusting dosage of renally excreted medications.
  • Monitoring renal transplant recipients.
Estimated Glomerular Filtration Rate (eGFR):
  • Serum creatinine measurement is used in estimating GFR for people with chronic kidney disease (CKD) and those with risk factors for CKD (diabetes, hypertension, cardiovascular disease, and family history of kidney disease)
 
Methodology (วิธีการทดสอบ):
Enzymatic
 
AliasesName (ชื่อเรียกอื่นๆ) :
Creatinine
eGFR
Estimated glomerular filtration rate
 
 
 
Test Code (รหัสการทดสอบ):
CR

Order Name (ชื่อการทดสอบ):
Creatinine and eGFR

 
Collection Specimen Or Container (สิ่งส่งตรวจ/ภาชนะ):
Blood/ Plain blood (Red top) 6 mL, 1 tube
 
Specimen Testing Type (สิ่งส่งตรวจที่ใช้ในการทดสอบ):
Serum, minimum volume 0.5 mL
 
Sub Mission Container (ภาชนะส่งตรวจ):
Plastic vial
 
Specimen Stabillity (ความคงตัวของสิ่งส่งตรวจ):
Specimen Type Temperature Time
Serum Refrigerated, 2oC to 8oC 7 days
Frozen, -20o 3 months
 
 
 
Test Code (รหัสการทดสอบ):
CR

Order Name (ชื่อการทดสอบ):
Creatinine and eGFR

 
Method detail (วิธีการทดสอบ):
Enzymatic
 
Schedule (ตารางการทดสอบ):
Tested daily (24 hours)
 
Turnaround Time (ระยะเวลารอผล):
Collected specimen to report within 90 min
 
Performing Location (หน่วยงานที่ทำการทดสอบ):
Chemistry, Laboratory Department Tel. 13224
 
Specimen Retention Time (ระยะเวลาเก็บสิ่งส่งตรวจ):
5 days
 
 
 
Test Code (รหัสการทดสอบ):
CR

Order Name (ชื่อการทดสอบ):
Creatinine and eGFR

 
 
Clinical Information (ข้อมูลทางคลินิก):
Creatinine is eliminated from blood by glomerular filtration. Reduced renal function results in an increased serum creatinine concentration. Measurement of serum creatinine is used to diagnose and monitor acute and chronic renal disease, estimate glomerular filtration rate (GFR), or assess the status of renal dialysis patients. Urine creatinine analysis is used to calculate creatinine clearance, confirm completeness of 24-hour collections, or serve as a reference quantity for other analytes, such as in calculation of the albumin/creatinine ratio.
 
Reference Value (ค่าอ้างอิง):
Male : 0.73 –1.18 mg/dL
Female : 0.55 –1.02 mg/dL
 
Interpretation (การแปลผล):
Creatinine: Because serum creatinine is inversely correlated with glomerular filtration rate (GFR), when renal function is near normal, absolute changes in serum creatinine reflect larger changes than do similar absolute changes when renal function is poor. For example, an increase in serum creatinine from 1 to 2 mg/dL may indicate a decrease in GFR of 50 mL/min (from 100 to 50 mL/min), whereas an increase in serum creatinine level from 4 to 5 mg/dL may indicate a decrease of only 5 mL/min (from 25 to 20 mL/min). Because of the imprecision of serum creatinine as an assessment of GFR, there may be clinical situations where a more accurate GFR assessment must be performed, iothalamate or inulin clearance are superior to serum creatinine and eGFR. Several factors may influence serum creatinine independent of changes in GFR. For instance, creatinine generation is dependent upon muscle mass. Thus, young, muscular males may have significantly higher serum creatinine levels than elderly females, despite having similar GFRs. Also, because some renal clearance of creatinine is due to tubular secretion, drugs that inhibit this secretory component (eg, cimetidine and trimethoprim) may cause small increases in serum creatinine without an actual decrease in GFR.
 
Clinical Reference (เอกสารอ้างอิง):
  1. Manufacturer’s reagent package insert, Architect ® Creatinine (enzymatic), SENTINEL CH.SpA Via Robert Koch, 2 Milan 20152, Italy .
  2. http://www.mayomedicallaboratories.com (Retrieved: 01 Jan 2019) Establishment for Architect System (Year 2014)