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Clear
 
Test Code:
090-30-1963-01

Order Name:
Cocaine (Urine), EIA *

 
Useful For:
Determination of benzoylecgonine (cocaine metabolite) in human urine.  The assay is intended for use in clinical laboratories. This assay provides only a preliminary analytical test result. A more specific alternate chemical
method must be used to obtain a confirmed analytical result. Gas Chromatography/Mass Spectrometry (GC/MS) is the preferred confirmatory method. Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are used.
 
Methodology:
Enzyme immunoassay
 
 
 
Test Code:
090-30-1963-01

Order Name:
Cocaine (Urine), EIA *

 
Collection Specimen Or Container:
Urine, Clean container 
 
Specimen Testing Type:
Urine, minimum volume 10 mL
 
 
Sub Mission Container:
Clean container
 
Specimen Stabillity:
Specimen Type Temperature Time
Urine Refrigerated, 2oC to 8oC 5 days
 
 
 
Test Code:
090-30-1963-01

Order Name:
Cocaine (Urine), EIA *

 
Method detail:
Enzyme immunoassay
 
Schedule:
Tested daily (24 Hours)
 
Turnaround Time:
Collected specimen to report within 1.5 hours (90 mins)
 
Performing Location:
Chemistry, Laboratory Department
Tel. 13224
 
Specimen Retention Time:
7 days
 
 
 
Test Code:
090-30-1963-01

Order Name:
Cocaine (Urine), EIA *

 
 
Clinical Information:
Cocaine is a very common illicit drug. When ingested, it is rapidly metabolized and excreted into urine as benzoylecgonine (the major metabolite of cocaine) within four hours. Detection of benzoylecgonine
in urine indicates use of cocaine.
Excretion rate patterns vary with the mode of administration and from individual to individual. Cocaine is almost completely metabolized, primarily in the liver, with only about 1% to 9% excreted unchanged in the urine (dependent on urine pH). Thirty-five to fifty-four percent is eliminated as benzoylecgonine, the major metabolite of cocaine.
Cocaine is also excreted in relatively lesser amounts as ecgonine methyl ester (32% to 49%) and ecgonine. Cocaine metabolites may be detected in urine up to several days after cocaine use. Benzoylecgonine
can be detected in urine within four hours after cocaine inhalation and remain detectable in concentrations greater than 1,000 ng/mL for as long as 48 hours.
 
Reference Value:
Negative (Cut off <300 ng/mL)
 
Clinical Reference:
Manufacturer’s reagent package insert, Architect Cocaine, Microgenics Corporation 46500 Kato Road,
Fremont, CA 94538 USA, November 2017.